The DOI matches its Crossref record.
Ethanol Oxidation by Hepatic Microsomes: Adaptive Increase after Ethanol Feeding
Abstract
Hepatic microsomes contain an ethanol-oxidizing system distinct from alcohol dehydrogenase. In vitro, it has characteristics comparable to those of microsomal drug-detoxifying enzymes and, in vivo, it is capable of adaptation to the administration of ethanol. The existence of this microsomal ethanol-oxidizing system may explain ultrastructural, pharmacological, and biochemical effects of ethanol.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
P450 Enzymes: Their Structure, Reactivity, and Selectivity—Modeled by QM/MM Calculations
Shaik, S., Cohen, S., Wang, Y., Chen, H., Kumar, D., & Thiel, W. (2010) · Chemical Reviews · doi:10.1021/cr900121s · Cited by 1,083
Alcoholic Liver Disease: Pathogenesis and Current Management
Osna, N. (2017) · Alcohol Research: Current Reviews · doi:10.35946/arcr.v38.2.01 · Cited by 724
Alcoholic fatty liver: its pathogenesis and mechanism of progression to inflammation and fibrosis
Lieber, C. S. (2004) · Alcohol · doi:10.1016/j.alcohol.2004.07.008 · Cited by 699
Self-citationCYTOCHROME P450: Nature's Most Versatile Biological Catalyst
Coon, M. J. (2005) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.45.120403.100030 · Cited by 395
Inhibition and induction of human cytochrome P450 (CYP) enzymes
PELKONEN, O., MÄEENPÄEÄ, J., TAAVITSAINEN, P., RAUTIO, A., & RAUNIO, H. (1998) · Xenobiotica · doi:10.1080/004982598238886 · Cited by 358
Metadata
- Authors
- Lieber, C. S., & DeCarli, L. M.
- Venue
- Science
- Published
- 1968-11-22
- Volume
- 162
- Issue
- 3856
- Pages
- 917-918
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2020267550
- Cited by
- 556
- References
- 0
- FWCI
- 51.80
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Ethanol Oxidation by Hepatic Microsomes: Adaptive Increase after Ethanol Feeding. https://app.cochat.ai/papers/10.1126/science.162.3856.917
- The paper
- Lieber, C. S., & DeCarli, L. M. (1968). Ethanol Oxidation by Hepatic Microsomes: Adaptive Increase after Ethanol Feeding. Science. https://doi.org/10.1126/science.162.3856.917
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
