The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Magnetoferritin: in Vitro Synthesis of a Novel Magnetic Protein
Open accessAbstract
The iron storage protein ferritin consists of a spherical polypeptide shell (apoferritin) surrounding a 6-nanometer inorganic core of the hydrated iron oxide ferrihydrite (5Fe 2 O 3 ⋅9H 2 O). Previous studies have shown that the in vitro reconstitution of apoferritin yields mineral cores essentially identical to those of the native proteins. A magnetic mineral was synthesized within the nanodimensional cavity of horse spleen ferritin by the use of controlled reconstitution conditions. Transmission electron microscopy and electron diffraction analysis indicate that the entrapped mineral particles are discrete 6-nanometer spherical single crystals of the ferrimagnetic iron oxide magnetite (Fe 3 O 4 ). The resulting magnetic protein, "magnetoferritin," could have uses in biomedical imaging, cell labeling, and separation procedures.
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Cites
Solving the structure of human H ferritin by genetically engineering intermolecular crystal contacts
Lawson, D. M., Artymiuk, P. J., Yewdall, S. J., Smith, J. M. A., Livingstone, J. C., Treffry, A., Luzzago, A., Levi, S., Arosio, P., Cesareni, G., et al. (1991) · Nature · doi:10.1038/349541a0 · Cited by 777
Identification of the ferroxidase centre in ferritin
Lawson, D. M., Treffry, A., Artymiuk, P. J., Harrison, P. M., Yewdall, S. J., Luzzago, A., Cesareni, G., Levi, S., & Arosio, P. (1989) · FEBS Letters · doi:10.1016/0014-5793(89)81040-3 · Cited by 312
Cited by
Laurent, S., Forge, D., Port, M., Roch, A., Robic, C., Vander Elst, L., & Muller, R. N. (2008) · Chemical Reviews · doi:10.1021/cr068445e · Cited by 6,852
The ferritins: molecular properties, iron storage function and cellular regulation
Harrison, P. M., & Arosio, P. (1996) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/0005-2728(96)00022-9 · Cited by 2,667
Iron oxide MR contrast agents for molecular and cellular imaging
Bulte, J. W. M., & Kraitchman, D. L. (2004) · NMR in Biomedicine · doi:10.1002/nbm.924 · Cited by 1,500
Potential toxicity of superparamagnetic iron oxide nanoparticles (SPION)
Singh, N., Jenkins, G. J. S., Asadi, R., & Doak, S. H. (2010) · Nano Reviews · doi:10.3402/nano.v1i0.5358 · Cited by 1,112
Liu, J.-F., Zhao, Z.-S., & Jiang, G.-B. (2008) · Environmental Science & Technology · doi:10.1021/es800924c · Cited by 1,084
Metadata
- Authors
- Meldrum, F. C., Heywood, B. R., & Mann, S.
- Venue
- Science
- Published
- 1992-07-24
- Volume
- 257
- Issue
- 5069
- Pages
- 522-523
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2097794761
- Cited by
- 572
- References
- 2
- FWCI
- 10.24
- Type
- journal article
- Language
- en
- Open access
- green
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- Meldrum, F. C., Heywood, B. R., & Mann, S. (1992). Magnetoferritin: in Vitro Synthesis of a Novel Magnetic Protein. Science. https://doi.org/10.1126/science.1636086
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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