The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
An Inducible Bundle-Forming Pilus of Enteropathogenic Escherichia coli
Abstract
Enteropathogenic Escherichia coli (EPEC), a cause of childhood diarrhea, grow on the surface of the small intestine and on cultured epithelial cells as colonies of adherent bacteria. When propagated on solid medium containing blood or attached to HEp-2 cells, EPEC express ropelike bundles of filaments, termed bundle-forming pili (BFP), that create a network of fibers that bind together the individual organisms. BFP were found to be expressed by five EPEC serogroups, each harboring a ∼92-kilobase plasmid previously known to be important for virulence in humans. When two of these strains were cured of this plasmid, they neither expressed BFP nor grew as adherent colonies. An antiserum to BFP reduced the capacity of EPEC to infect cultured epithelial cells. BFP are composed of a repeating subunit of 19,500 daltons, the amino-terminal amino acid sequence of this subunit is homologous to that of the toxin-coregulated pilin of Vibrio cholerae .
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Cites
Bradford, M. M. (1976) · Analytical Biochemistry · doi:10.1016/0003-2697(76)90527-3 · Cited by 255,302
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
LAEMMLI, U. K. (1970) · Nature · doi:10.1038/227680a0 · Cited by 249,961
Cited by
Kaper, J. B., Nataro, J. P., & Mobley, H. L. T. (2004) · Nature Reviews Microbiology · doi:10.1038/nrmicro818 · Cited by 5,583
Type IV Pili, Transient Bacterial Aggregates, and Virulence of Enteropathogenic Escherichia coli
Bieber, D., Ramer, S. W., Wu, C.-Y., Murray, W. J., Tobe, T., Fernandez, R., & Schoolnik, G. K. (1998) · Science · doi:10.1126/science.280.5372.2114 · Cited by 465
Self-citationHobbs, M., & Mattick, J. S. (1993) · Molecular Microbiology · doi:10.1111/j.1365-2958.1993.tb01949.x · Cited by 371
The flagella of enteropathogenic Escherichia coli mediate adherence to epithelial cells
Girón, J. A., Torres, A. G., Freer, E., & Kaper, J. B. (2002) · Molecular Microbiology · doi:10.1046/j.1365-2958.2002.02899.x · Cited by 363
Self-citationNataro, J. P., Deng, Y., Maneval, D. R., German, A. L., Martin, W. C., & Levine, M. M. (1992) · Infection and Immunity · doi:10.1128/iai.60.6.2297-2304.1992 · Cited by 303
Metadata
- Authors
- Girón, J. A., Ho, A. S. Y., & Schoolnik, G. K.
- Venue
- Science
- Published
- 1991-11
- Volume
- 254
- Issue
- 5032
- Pages
- 710-713
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2021369351
- Cited by
- 604
- References
- 2
- FWCI
- 11.75
- Type
- journal article
- Language
- en
- Open access
- closed
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- Girón, J. A., Ho, A. S. Y., & Schoolnik, G. K. (1991). An Inducible Bundle-Forming Pilus of Enteropathogenic Escherichia coli. Science. https://doi.org/10.1126/science.1683004
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
