The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Retroviral Recombination and Reverse Transcription
Abstract
Recombination occurs at a high rate in retroviral replication, and its observation requires a virion containing two different RNA molecules (heterodimeric particles). Analysis of retroviral recombinants formed after a single round of replication revealed that (i) the nonselected markers changed more frequently than expected from the rate of recombination of selected markers; (ii) the transfer of the initially synthesized minus strand strong stop DNA was either intramolecular or intermolecular; (iii) the transfer of the first synthesized plus strand strong stop DNA was always intramolecular; and (iv) there was a strong correlation between the type of transfer of the minus strand strong stop DNA and the number of template switches observed. These data suggest that retroviral recombination is ordered and occurs during the synthesis of both minus and plus strand DNA.
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Citations
Cites
A detailed model of reverse transcription and tests of crucial aspects
Gilboa, E., Mitra, S. W., Goff, S., & Baltimore, D. (1979) · Cell · doi:10.1016/0092-8674(79)90357-x · Cited by 612
Structure, variation and synthesis of retrovirus long terminal repeat
TEMIN, H. (1981) · Cell · doi:10.1016/0092-8674(81)90353-6 · Cited by 237
Self-citation
Cited by
Mansky, L. M., & Temin, H. M. (1995) · Journal of Virology · doi:10.1128/jvi.69.8.5087-5094.1995 · Cited by 1,154
Self-citationRobertson, D. L., Anderson, J. P., Bradac, J. A., Carr, J. K., Foley, B., Funkhouser, R. K., Gao, F., Hahn, B. H., Kalish, M. L., Kuiken, C., et al. (2000) · Science · doi:10.1126/science.288.5463.55d · Cited by 964
Crystal structure of the ribonuclease H domain of HIV-1 reverse transcriptase
Davies, J. F., Hostomska, Z., Hostomsky, Z., Jordan, S. R., & Matthews, D. A. (1991) · Science · doi:10.1126/science.1707186 · Cited by 570
Robertson, D. L., Hahn, B. H., & Sharp, P. M. (1995) · Journal of Molecular Evolution · doi:10.1007/bf00163230 · Cited by 423
High Rate of Recombination throughout the Human Immunodeficiency Virus Type 1 Genome
Jetzt, A. E., Yu, H., Klarmann, G. J., Ron, Y., Preston, B. D., & Dougherty, J. P. (2000) · Journal of Virology · doi:10.1128/jvi.74.3.1234-1240.2000 · Cited by 379
Metadata
- Authors
- Hu, W.-S., & Temin, H. M.
- Venue
- Science
- Published
- 1990-11-30
- Volume
- 250
- Issue
- 4985
- Pages
- 1227-1233
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2027051533
- Cited by
- 598
- References
- 2
- FWCI
- 6.68
- Type
- journal article
- Language
- en
- Open access
- closed
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- Hu, W.-S., & Temin, H. M. (1990). Retroviral Recombination and Reverse Transcription. Science. https://doi.org/10.1126/science.1700865
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
