The DOI matches its Crossref record.
Acetylcholine Liberation from Cerebral Cortex during Paradoxical (REM) Sleep
Abstract
The rate of liberation of free acetylcholine from the surface of prostigmin-treated cerebral cortex in the freely moving cat has been determined in states of slow wave sleep, paradoxical or activated sleep, and waking. The average rate during slow wave sleep (1.2 nanograms per minute per square centimeter of cortical surface) increased during paradoxical sleep (2.2 nanograms per minute) and during waking (2.1 nanograms per minute). The rate of acetylcholine release is thus related to the electroencephalogram pattern of desynchronized activation of the cortex rather than to the behavioral responsiveness of the animals.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Alzheimer's disease: Targeting the Cholinergic System
H. Ferreira-Vieira, T., M. Guimaraes, I., R. Silva, F., & M. Ribeiro, F. (2016) · Current Neuropharmacology · doi:10.2174/1570159x13666150716165726 · Cited by 1,551
Control of sleep and wakefulness
Brown, R. E., Basheer, R., McKenna, J. T., Strecker, R. E., & McCarley, R. W. (2012) · Physiological Reviews · doi:10.1152/physrev.00032.2011 · Cited by 1,477
Natural waking and sleep states: a view from inside neocortical neurons
Steriade, M., Timofeev, I., & Grenier, F. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.85.5.1969 · Cited by 1,296
General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal
Franks, N. P. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2372 · Cited by 1,295
Dependence on REM Sleep of Overnight Improvement of a Perceptual Skill
Karni, A., Tanne, D., Rubenstein, B. S., Askenasy, J. J. M., & Sagi, D. (1994) · Science · doi:10.1126/science.8036518 · Cited by 1,002
Metadata
- Authors
- Jasper, H. H., & Tessier, J.
- Venue
- Science
- Published
- 1971-05-07
- Volume
- 172
- Issue
- 3983
- Pages
- 601-602
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2020690996
- Cited by
- 426
- References
- 0
- FWCI
- 5.69
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Acetylcholine Liberation from Cerebral Cortex during Paradoxical (REM) Sleep. https://app.cochat.ai/papers/10.1126/science.172.3983.601
- The paper
- Jasper, H. H., & Tessier, J. (1971). Acetylcholine Liberation from Cerebral Cortex during Paradoxical (REM) Sleep. Science. https://doi.org/10.1126/science.172.3983.601
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
