The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Polyadenylic Acid Sequences: Role in Conversion of Nuclear RNA into Messenger RNA
Abstract
Polyadenylic acid [poly(A)] segments containing 150 to 250 nucleotides appear to be covalently linked to heterogeneous nuclear RNA (HnRNA) and messenger RNA (mRNA) in eucaryotic cells. The poly(A) is synthesized in the nucleus, and is probably linked initially to HnRNA that is ultimately transported as mRNA to the cytoplasm. Studies with inhibitors of RNA or poly(A) synthesis indicate that synthesis of poly(A) segments is independent of transcription. The poly(A) marker may prove useful to elucidate mRNA modification and transport in eucaryotic cells.
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Edmonds, M., Vaughan, M. H., & Nakazato, H. (1971) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.68.6.1336 · Cited by 510
Cited by
Organization, Transcription, and Regulation in the Animal Genome
Davidson, E. H., & Britten, R. J. (1973) · The Quarterly Review of Biology · doi:10.1086/407817 · Cited by 451
Berger, S. L., & Birkenmeier, C. S. (1979) · Biochemistry · doi:10.1021/bi00590a018 · Cited by 443
Determinants and implications of mRNA poly(A) tail size – Does this protein make my tail look big?
Jalkanen, A. L., Coleman, S. J., & Wilusz, J. (2014) · Seminars in Cell & Developmental Biology · doi:10.1016/j.semcdb.2014.05.018 · Cited by 154
Meiotic maturation in Xenopus requires polyadenylation of multiple mRNAs
Barkoff, A., Ballantyne, S., & Wickens, M. (1998) · The EMBO Journal · doi:10.1093/emboj/17.11.3168 · Cited by 93
Metadata
- Authors
- Darnell, J. E., Philipson, L., Wall, R., & Adesnik, M.
- Venue
- Science
- Published
- 1971-10-29
- Volume
- 174
- Issue
- 4008
- Pages
- 507-510
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2081034153
- Cited by
- 563
- References
- 1
- FWCI
- 45.76
- Type
- journal article
- Language
- en
- Open access
- closed
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- Darnell, J. E., Philipson, L., Wall, R., & Adesnik, M. (1971). Polyadenylic Acid Sequences: Role in Conversion of Nuclear RNA into Messenger RNA. Science. https://doi.org/10.1126/science.174.4008.507
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
