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Flagellar Movement: A Sliding Filament Model: An explanation is suggested for the spontaneous propagation of bending waves by flagella.

Brokaw, Charles J.·1972·Science

Abstract

A sliding filament mechanism appears to provide the most satisfactory basis for a simple feedback mechanism for the control of bend propagation and bend initiation by flagella, and is supported by strong experimental evidence. A computer simulation of the movements of a flagellar model based on the sliding filament mechanism demonstrates that this mechanism offers a sufficient explanation for the automatic generation of flagellar bending waves. Further computer simulation studies may provide insight into questions such as the applicability of the sliding filament mechanism to the generation of the more complicated asymmetrical bending patterns of cilia, and the control of the bending pattern by interaction between several sliding filament systems within a flagellum.

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Metadata

Authors
Brokaw, C. J.
Venue
Science
Published
1972-11-03
Volume
178
Issue
4060
Pages
455-462
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2057481524
Cited by
195
References
0
FWCI
7.43
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Flagellar Movement: A Sliding Filament Model: An explanation is suggested for the spontaneous propagation of bending waves by flagella. https://app.cochat.ai/papers/10.1126/science.178.4060.455
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Brokaw, C. J. (1972). Flagellar Movement: A Sliding Filament Model: An explanation is suggested for the spontaneous propagation of bending waves by flagella. Science. https://doi.org/10.1126/science.178.4060.455

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.