The DOI matches its Crossref record; 178 of the 178 references it cites were found in a registry or an index.
Sperm flagella: comparative and phylogenetic perspectives of protein components
Abstract
Sperm motility is necessary for the transport of male DNA to eggs in species with both external and internal fertilization. Flagella comprise several proteins for generating and regulating motility. Central cytoskeletal structures called axonemes have been well conserved through evolution. In mammalian sperm flagella, two accessory structures (outer dense fiber and the fibrous sheath) surround the axoneme. The axonemal bend movement is based on the active sliding of axonemal doublet microtubules by the molecular motor dynein, which is divided into outer and inner arm dyneins according to positioning on the doublet microtubule. Outer and inner arm dyneins play different roles in the production and regulation of flagellar motility. Several regulatory mechanisms are known for both dyneins, which are important in motility activation and chemotaxis at fertilization. Although dynein itself has certain properties that contribute to the formation and propagation of flagellar bending, other axonemal structures-specifically, the radial spoke/central pair apparatus-have essential roles in the regulation of flagellar bending. Recent genetic and proteomic studies have explored several new components of axonemes and shed light on the generation and regulation of sperm motility during fertilization.
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Cites
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The Molecular Architecture of Axonemes Revealed by Cryoelectron Tomography
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Post-translational modifications regulate microtubule function
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Adenosine Triphosphate-Induced Sliding of Tubules in Trypsin-Treated Flagella of Sea-Urchin Sperm
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Cited by
Teratozoospermia: spotlight on the main genetic actors in the human
Coutton, C., Escoffier, J., Martinez, G., Arnoult, C., & Ray, P. F. (2015) · Human Reproduction Update · doi:10.1093/humupd/dmv020 · Cited by 352
Formation and function of sperm tail structures in association with sperm motility defects†
Lehti, M. S., & Sironen, A. (2017) · Biology of Reproduction · doi:10.1093/biolre/iox096 · Cited by 267
The functional anatomy of the human spermatozoon: relating ultrastructure and function
Mortimer, D. (2018) · MHR: Basic science of reproductive medicine · doi:10.1093/molehr/gay040 · Cited by 63
PITHD1 is a proteasome-interacting protein essential for male fertilization
Kondo, H., Matsumura, T., Kaneko, M., Inoue, K., Kosako, H., Ikawa, M., Takahama, Y., & Ohigashi, I. (2020) · Journal of Biological Chemistry · doi:10.1074/jbc.ra119.011144 · Cited by 17
(2023) · doi:10.1101/2023.02.25.530050 · Cited by 8
Metadata
- Authors
- Inaba, K.
- Venue
- Molecular Human Reproduction
- Publisher
- Oxford University Press (OUP)
- Published
- 2011-05-17
- Volume
- 17
- Issue
- 8
- Pages
- 524-538
- ISSN
- 1360-9947 (ISSN-L)
- 1460-2407
- OpenAlex
- W2154228764
- Cited by
- 287
- References
- 178
- FWCI
- 16.70
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
