The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Separation of IL-4 Production from Th Cell Proliferation by an Altered T Cell Receptor Ligand
Abstract
In the presence of antigen presenting cells, a murine T helper (Th) cell specific for murine hemoglobin (Hb) responded to its immunogenic peptide by both cytokine (interleukin-4) secretion and proliferation. An altered Hb peptide with a single amino acid substitution induced only cytokine secretion and did not induce proliferation. Interleukin-1 costimulated and restored the Th proliferative response to normal levels. The altered peptide also supported cognate T cell-B cell interactions indicative of T cell helper function. Thus, this result suggests that the T cell receptor has the capacity of differential signaling.
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A cell culture model for T lymphocyte clonal anergy
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Self-citationJenkins, M. K., & Schwartz, R. H. (1987) · The Journal of experimental medicine · doi:10.1084/jem.165.2.302 · Cited by 1,170
Contingent Genetic Regulatory Events in T Lymphocyte Activation
Crabtree, G. R. (1989) · Science · doi:10.1126/science.2783497 · Cited by 1,072
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Self-citationKurt-Jones, E. A., Hamberg, S., Ohara, J., Paul, W. E., & Abbas, A. K. (1987) · The Journal of experimental medicine · doi:10.1084/jem.166.6.1774 · Cited by 280
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Constantinescu, C. S., Farooqi, N., O'Brien, K., & Gran, B. (2011) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2011.01302.x · Cited by 1,523
Tarke, A., Sidney, J., Methot, N., Yu, E. D., Zhang, Y., Dan, J. M., Goodwin, B., Rubiro, P., Sutherland, A., Wang, E., et al. (2021) · Cell Reports Medicine · doi:10.1016/j.xcrm.2021.100355 · Cited by 706
Development and Selection of T Cells: Facts and Puzzles
Kisielow, P., & Von Boehmer, H. (1995) · Advances in Immunology · doi:10.1016/s0065-2776(08)60620-3 · Cited by 444
Prokhnevska, N., Cardenas, M. A., Valanparambil, R. M., Sobierajska, E., Barwick, B. G., Jansen, C., Reyes Moon, A., Gregorova, P., delBalzo, L., Greenwald, R., et al. (2023) · Immunity · doi:10.1016/j.immuni.2022.12.002 · Cited by 365
Kita, H., Matsumura, S., He, X.-S., Ansari, A. A., Lian, Z.-X., Van de Water, J., Coppel, R. L., Kaplan, M. M., & Gershwin, M. E. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0214698 · Cited by 222
Metadata
- Authors
- Evavold, B. D., & Allen, P. M.
- Venue
- Science
- Published
- 1991-05-31
- Volume
- 252
- Issue
- 5010
- Pages
- 1308-1310
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2032169064
- Cited by
- 549
- References
- 12
- FWCI
- 10.32
- Type
- journal article
- Language
- en
- Open access
- closed
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- Evavold, B. D., & Allen, P. M. (1991). Separation of IL-4 Production from Th Cell Proliferation by an Altered T Cell Receptor Ligand. Science. https://doi.org/10.1126/science.1833816
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
