The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Conformation of [Leu5]Enkephalin from X-Ray Diffraction: Features Important for Recognition at Opiate Receptor
Abstract
The conformation of [Leu 5]enkephalin is produced by a Tyr-Gly-Gly-Phe β bend stabilized by antiparallel hydrogen bonding between tyrosine and phenylalanine. On the basis of a comparison of the observed structure with the structure of known opiate agonists, three hydrophilic and two hydrophobic regions have been identified as contributing to the recognition of the molecule at the opiate receptor site.
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Citations
Cites
Identification of two related pentapeptides from the brain with potent opiate agonist activity
Hughes, J., Smith, T. W., Kosterlitz, H. W., Fothergill, L. A., Morgan, B. A., & Morris, H. R. (1975) · Nature · doi:10.1038/258577a0 · Cited by 3,806
Cited by
Takahashi, O., Kohno, Y., & Nishio, M. (2010) · Chemical Reviews · doi:10.1021/cr100072x · Cited by 583
Reverse Turns in Peptides and Protein
Smith, J. A., Pease, L. G., & Kopple, K. D. (1980) · Critical Reviews in Biochemistry · doi:10.3109/10409238009105470 · Cited by 501
Bleiholder, C., Dupuis, N. F., Wyttenbach, T., & Bowers, M. T. (2011) · Nature Chemistry · doi:10.1038/nchem.945 · Cited by 366
Metadata
- Authors
- Smith, G. D., & Griffin, J. F.
- Venue
- Science
- Published
- 1978-03-17
- Volume
- 199
- Issue
- 4334
- Pages
- 1214-1216
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2042687048
- Cited by
- 245
- References
- 1
- FWCI
- 6.23
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Conformation of [Leu5]Enkephalin from X-Ray Diffraction: Features Important for Recognition at Opiate Receptor. https://app.cochat.ai/papers/10.1126/science.204006
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- Smith, G. D., & Griffin, J. F. (1978). Conformation of [Leu5]Enkephalin from X-Ray Diffraction: Features Important for Recognition at Opiate Receptor. Science. https://doi.org/10.1126/science.204006
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
