The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
Two Distinct Transcription Factors that Bind the Immunoglobulin Enhancer μE5/κE2 Motif
Abstract
Activity of the immunoglobulin heavy and κ light chain gene enhancers depends on a complex interplay of ubiquitous and developmentally regulated proteins. Two complementary DNAs were isolated that encode proteins, denoted ITF-1 and ITF-2, that are expressed in a variety of cell types and bind the μE5/κE2 motif found in both heavy and κ light chain enhancers. The complementary DNAs are the products of distinct genes, yet both ITF-1 and ITF-2 are structurally and functionally similar. The two proteins interact with one another through their putative helix-loop-helix motifs and each possesses a distinct domain that dictates transcription activation.
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Cites
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Cited by
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Metadata
- Authors
- Henthorn, P., Kiledjian, M., & Kadesch, T.
- Venue
- Science
- Published
- 1990-01-26
- Volume
- 247
- Issue
- 4941
- Pages
- 467-470
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1989297216
- Cited by
- 462
- References
- 35
- FWCI
- 16.61
- Type
- journal article
- Language
- en
- Open access
- closed
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- Henthorn, P., Kiledjian, M., & Kadesch, T. (1990). Two Distinct Transcription Factors that Bind the Immunoglobulin Enhancer μE5/κE2 Motif. Science. https://doi.org/10.1126/science.2105528
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
