The DOI matches its Crossref record.
Feedback Inhibition of Brain Noradrenaline Neurons by Tricyclic Antidepressants: α-Receptor Mediation
Abstract
The use of different receptor blocking agents and single-unit recording techniques indicates that feedback inhibition of brain noradrenaline neurons by tricyclic antidepressants is mediated by presynaptic α-receptors. After chronic imipramine treatment, noradrenaline neurons in the locus coeruleus of rat brain remained partly depressed, in agreement with clinical data. They were, however, resistant to further inhibition by imipramine or clonidine.
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Citations
Cited by
Charney, D. S. (1981) · Archives of General Psychiatry · doi:10.1001/archpsyc.1981.01780350094011 · Cited by 649
Charney, D. S. (1984) · Archives of General Psychiatry · doi:10.1001/archpsyc.1984.01790190025003 · Cited by 599
Phase Advance of the Circadian Sleep-Wake Cycle as an Antidepressant
Wehr, T. A., Wirz-Justice, A., Goodwin, F. K., Duncan, W., & Gillin, J. C. (1979) · Science · doi:10.1126/science.227056 · Cited by 528
Single unit activity of locus coeruleus neurons in the freely moving cat
Rasmussen, K., Morilak, D. A., & Jacobs, B. L. (1986) · Brain Research · doi:10.1016/0006-8993(86)90370-7 · Cited by 324
Morgan, V (2005) · Gut · doi:10.1136/gut.2004.047423 · Cited by 269
Metadata
- Authors
- Svensson, T. H., & Usdin, T.
- Venue
- Science
- Published
- 1978-12-08
- Volume
- 202
- Issue
- 4372
- Pages
- 1089-1091
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1999756751
- Cited by
- 397
- References
- 0
- FWCI
- 7.92
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Feedback Inhibition of Brain Noradrenaline Neurons by Tricyclic Antidepressants: α-Receptor Mediation. https://app.cochat.ai/papers/10.1126/science.213833
- The paper
- Svensson, T. H., & Usdin, T. (1978). Feedback Inhibition of Brain Noradrenaline Neurons by Tricyclic Antidepressants: α-Receptor Mediation. Science. https://doi.org/10.1126/science.213833
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
