The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
HSP104 Required for Induced Thermotolerance
Abstract
A heat shock protein gene, HSP104 , was isolated from Saccharomyces cerevisiae and a deletion mutation was introduced into yeast cells. Mutant cells grew at the same rate as wild-type cells and died at the same rate when exposed directly to high temperatures. However, when given a mild pre-heat treatment, the mutant cells did not acquire tolerance to heat, as did wild-type cells. Transformation with the wild-type gene rescued the defect of mutant cells. The results demonstrate that a particular heat shock protein plays a critical role in cell survival at extreme temperatures.
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Cites
Borkovich, K. A., Farrelly, F. W., Finkelstein, D. B., Taulien, J., & Lindquist, S. (1989) · Molecular and Cellular Biology · doi:10.1128/mcb.9.9.3919 · Cited by 641
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Verghese, J., Abrams, J., Wang, Y., & Morano, K. A. (2012) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.05018-11 · Cited by 575
Stress tolerance: The key to effective strains of industrial baker's yeast
Attfield, P. V. (1997) · Nature Biotechnology · doi:10.1038/nbt1297-1351 · Cited by 461
Cellular Handling of Protein Aggregates by Disaggregation Machines
Mogk, A., Bukau, B., & Kampinga, H. H. (2018) · Molecular Cell · doi:10.1016/j.molcel.2018.01.004 · Cited by 365
Hsp104 and ClpB: protein disaggregating machines
Doyle, S. M., & Wickner, S. (2009) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2008.09.010 · Cited by 284
Duina, A. A., Kalton, H. M., & Gaber, R. F. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.30.18974 · Cited by 143
Metadata
- Authors
- Sanchez, Y., & Lindquist, S. L.
- Venue
- Science
- Published
- 1990-06
- Volume
- 248
- Issue
- 4959
- Pages
- 1112-1115
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2032625890
- Cited by
- 832
- References
- 1
- FWCI
- 11.62
- Type
- journal article
- Language
- en
- Open access
- closed
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