The DOI matches its Crossref record.
Specific Nonopiate Receptors for β-Endorphin
Abstract
Iodinated β H -[2-D-alanine]endorphin exhibits specific binding to cultured human lymphocytes. The binding is inhibited by low concentrations of β-endorphin and its D-alanine 2 derivative, but is not affected by opiate agonists and antagonists, or by enkephalin analogs, β-lipotropin, adrenocorticotrophic hormone, or α-melanocyte-stimulating hormone; this suggests the existence of a specific, nonopiate binding site (receptor) for β-endorphin. The carboxy-terminal region of β-endorphin is essential for this binding activity, since α-endorphin is not active. β-Endorphin may be a circulating hormone with peripheral physiological effects that are not primarily mediated through interactions with opiate or enkephalin receptors.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Mu Opioids and Their Receptors: Evolution of a Concept
Pasternak, G. W., & Pan, Y.-X. (2013) · Pharmacological Reviews · doi:10.1124/pr.112.007138 · Cited by 578
Jemmott, J. B., & Locke, S. E. (1984) · Psychological Bulletin · doi:10.1037//0033-2909.95.1.78 · Cited by 469
Laudenslager, M. L., Ryan, S. M., Drugan, R. C., Hyson, R. L., & Maier, S. F. (1983) · Science · doi:10.1126/science.6603018 · Cited by 444
Itching after epidural and spinal opiates
Ballantyne, J. C., Loach, A. B., & Carr, D. B. (1988) · Pain · doi:10.1016/0304-3959(88)90085-1 · Cited by 393
Maes, M., Bosmans, E., Suy, E., Minner, B., & Raus, J. (1991) · Psychological Medicine · doi:10.1017/s0033291700020419 · Cited by 62
Metadata
- Authors
- Hazum, E., Chang, K.-J., & Cuatrecasas, P.
- Venue
- Science
- Published
- 1979-09-07
- Volume
- 205
- Issue
- 4410
- Pages
- 1033-1035
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2039245564
- Cited by
- 412
- References
- 0
- FWCI
- 2.35
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Specific Nonopiate Receptors for β-Endorphin. https://app.cochat.ai/papers/10.1126/science.224457
- The paper
- Hazum, E., Chang, K.-J., & Cuatrecasas, P. (1979). Specific Nonopiate Receptors for β-Endorphin. Science. https://doi.org/10.1126/science.224457
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
