The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Dissociation of gp120 from HIV-1 Virions Induced by Soluble CD4
Abstract
The CD4 antigen is the high affinity cellular receptor for the human immunodeficiency virus type-1 (HIV-1). Binding of recombinant soluble CD4 (sCD4) or the purified V1 domain of sCD4 to the surface glycoprotein gp120 on virions resulted in rapid dissociation of gp120 from its complex with the transmembrane glycoprotein gp41. This may represent the initial stage in virus-cell and cell-cell fusion. Shedding of gp120 from virions induced by sCD4 may also contribute to the mechanism by which these soluble receptor molecules neutralize HIV-1.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Skehel, J. J., Bayley, P. M., Brown, E. B., Martin, S. R., Waterfield, M. D., White, J. M., Wilson, I. A., & Wiley, D. C. (1982) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.79.4.968 · Cited by 726
pH-independent HIV entry into CD4-positive T cells via virus envelope fusion to the plasma membrane
Stein, B. S., Gowda, S. D., Lifson, J. D., Penhallow, R. C., Bensch, K. G., & Engleman, E. G. (1987) · Cell · doi:10.1016/0092-8674(87)90542-3 · Cited by 627
Fine structure of human immunodeficiency virus (HIV) and immunolocalization of structural proteins
Gelderblom, H. R., Hausmann, E. H. S., Özel, M., Pauli, G., & Koch, M. A. (1987) · Virology · doi:10.1016/0042-6822(87)90449-1 · Cited by 521
Willey, R. L., Bonifacino, J. S., Potts, B. J., Martin, M. A., & Klausner, R. D. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.24.9580 · Cited by 428
Human immunodeficiency virus infection of CD4-bearing cells occurs by a pH-independent mechanism
McClure, M. O., Marsh, M., & Weiss, R. A. (1988) · The EMBO Journal · doi:10.1002/j.1460-2075.1988.tb02839.x · Cited by 295
Self-citation
Cited by
Wei, X., Decker, J. M., Liu, H., Zhang, Z., Arani, R. B., Kilby, J. M., Saag, M. S., Wu, X., Shaw, G. M., & Kappes, J. C. (2002) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.46.6.1896-1905.2002 · Cited by 1,569
VIRUS-CELL AND CELL-CELL FUSION
Hernandez, L. D., Hoffman, L. R., Wolfsberg, T. G., & White, J. M. (1996) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.12.1.627 · Cited by 567
Atomic structure of a thermostable subdomain of HIV-1 gp41
Tan, K., Liu, J.-H., Wang, J.-H., Shen, S., & Lu, M. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.23.12303 · Cited by 532
Quantitation of human immunodeficiency virus type 1 infection kinetics
Dimitrov, D. S., Willey, R. L., Sato, H., Chang, L. J., Blumenthal, R., & Martin, M. A. (1993) · Journal of Virology · doi:10.1128/jvi.67.4.2182-2190.1993 · Cited by 515
Wild, C., Oas, T., McDanal, C., Bolognesi, D., & Matthews, T. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.21.10537 · Cited by 485
Metadata
- Authors
- Moore, J. P., McKeating, J. A., Weiss, R. A., & Sattentau, Q. J.
- Venue
- Science
- Published
- 1990-11-23
- Volume
- 250
- Issue
- 4984
- Pages
- 1139-1142
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1986865717
- Cited by
- 576
- References
- 5
- FWCI
- 14.61
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Dissociation of gp120 from HIV-1 Virions Induced by Soluble CD4. https://app.cochat.ai/papers/10.1126/science.2251501
- The paper
- Moore, J. P., McKeating, J. A., Weiss, R. A., & Sattentau, Q. J. (1990). Dissociation of gp120 from HIV-1 Virions Induced by Soluble CD4. Science. https://doi.org/10.1126/science.2251501
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
