Why Nature Chose Phosphates

Westheimer, F. H.·1987·Science

Cited by (1,000)

Items 101–200 of 1,000

  1. Anion‐Coordination‐Induced Turn‐On Fluorescence of an Oligourea‐Functionalized Tetraphenylethene in a Wide Concentration Range
    Jie Zhao, Dong Yang, Yanxia Zhao, Xiao‐Juan Yang, Yao‐Yu Wang, Biao Wu · 2014 · Angewandte Chemie International Edition
  2. Automated Analysis of Nanomolar Concentrations of Phosphate in Natural Waters with Liquid Waveguide
    Jia‐Zhong Zhang, Jie Chi · 2002 · Environmental Science & Technology
  3. Role of Calcium in Central Nervous System Injuries
    W Young · 1992 · Journal of Neurotrauma
  4. Metals in Cyanobacteria: Analysis of the Copper, Nickel, Cobalt and Arsenic Homeostasis Mechanisms
    María José Huertas, Luis López‐Maury, Joaquín Giner‐Lamia, Ana María Sánchez-Riego, Francisco Javier Florencio · 2014 · Life
  5. Considering Protonation as a Posttranslational Modification Regulating Protein Structure and Function
    André Schönichen, Bradley A. Webb, Matthew P. Jacobson, Diane L. Barber · 2013 · Annual Review of Biophysics
  6. Calcium wave signaling in cancer cells
    Jai Parkash, Kamlesh Asotra · 2010 · Life Sciences
  7. An Exceptionally Mild Catalytic Thioester Aldol Reaction Inspired by Polyketide Biosynthesis
    Gojko Lalić, Allen D. Aloise, Matthew D. Shair · 2003 · Journal of the American Chemical Society
  8. Thermodynamic constraints shape the structure of carbon fixation pathways
    Arren Bar‐Even, Avi I. Flamholz, Εlad Noor, Ron Milo · 2012 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
  9. Specific Reaction Parametrization of the AM1/d Hamiltonian for Phosphoryl Transfer Reactions: H, O, and P Atoms
    Kwangho Nam, Qiang Cui, Jiali Gao, Darrin M. York · 2007 · Journal of Chemical Theory and Computation
  10. The Global Phosphorus Cycle
    Kathleen C. Ruttenberg · 2013 · Elsevier eBooks
  11. Protein kinase biochemistry and drug discovery
    Phillip A. Schwartz, Brion William Murray · 2011 · Bioorganic Chemistry
  12. Bioinspired Thiophosphorodichloridate Reagents for Chemoselective Histidine Bioconjugation
    Shang Jia, Dan He, Christopher J. Chang · 2019 · Journal of the American Chemical Society
  13. The microbial phosphorus cycle in aquatic ecosystems
    Solange Duhamel · 2024 · Nature Reviews Microbiology
  14. Stereochemistry of RNA Cleavage by the Tetrahymena Ribozyme and Evidence that the Chemical Step Is Not Rate-Limiting
    James A. McSwiggen, Thomas R. Cech · 1989 · Science
  15. Semipermeable lipid bilayers exhibit diastereoselectivity favoring ribose
    Sacerdote, M. G., Szostak, J. W. · 2005 · Proceedings of the National Academy of Sciences
  16. Detection of phosphates originating from Enceladus’s ocean
    Postberg, Frank, Sekine, Yasuhito, Klenner, Fabian, Glein, Christopher R., Zou, Zenghui, Abel, Bernd, Furuya, Kento, Hillier, Jon K., Khawaja, Nozair, Kempf, Sascha et al. · 2023 · Nature
  17. Prebiotic condensation through wet–dry cycling regulated by deliquescence
    Campbell, Thomas D., Febrian, Rio, McCarthy, Jack T., Kleinschmidt, Holly E., Forsythe, Jay G., Bracher, Paul J. · 2019 · Nature Communications
  18. A Simple Copper(II)− l -Histidine System for Efficient Hydrolytic Cleavage of DNA
    Rui Ren, Pin Yang, Weijuan Zheng, Zichun Hua · 2000 · Inorganic Chemistry
  19. Diphosphoinositol Polyphosphates: Metabolic Messengers?
    Stephen B. Shears · 2009 · Molecular Pharmacology
  20. The Role of Biomacromolecular Crowding, Ionic Strength, and Physicochemical Gradients in the Complexities of Life's Emergence
    Jan J. Spitzer, Bert Poolman · 2009 · Microbiology and Molecular Biology Reviews
  21. Recent Progress on Cellulose‐Based Ionic Compounds for Biomaterials
    Yang Yang, Yi‐Tung Lu, Kui Zeng, Thomas J. Heinze, Thomas Groth, Kai Zhang · 2020 · Advanced Materials
  22. Crystallization and structure determination of a hepatitis delta virus ribozyme: use of the RNA-binding protein U1A as a crystallization module
    Adrian R. Ferré-D’Amaré, Jennifer A. Doudna · 2000 · Journal of Molecular Biology
  23. Chemical fuels for molecular machinery
    Stefan Borsley, David A. Leigh, Benjamin M. W. Roberts · 2022 · Nature Chemistry
  24. Copper(II) Macrocycles Cleave Single-Stranded and Double-Stranded DNA under Both Aerobic and Anaerobic Conditions
    Eric L. Hegg, Judith N. Burstyn · 1996 · Inorganic Chemistry
  25. Driving the cell cycle through metabolism
    Cai, Ling, Tu, Benjamin P. · 2012 · Annual Review of Cell and Developmental Biology
  26. Vanadium–phosphatase complexes: Phosphatase inhibitors favor the trigonal bipyramidal transition state geometries
    C.C. McLauchlan, Benjamin Peters, Gail R. Willsky, Debbie C. Crans · 2015 · Coordination Chemistry Reviews
  27. Discovery of Pyrophosphate Diesters as Tunable, Soluble, and Bioorthogonal Linkers for Site-Specific Antibody–Drug Conjugates
    Jeffrey C. Kern, Mark T. Cancilla, Deborah Dooney, Kristen Kwasnjuk, Rena Zhang, Maribel Beaumont, Isabel Figueroa, SuChun Hsieh, Linda A. Liang, Daniela M. Tomazela et al. · 2016 · Journal of the American Chemical Society
  28. Synthesis, in vitro antibacterial and antifungal evaluations of new α-hydroxyphosphonate and new α-acetoxyphosphonate derivatives of tetrazolo [1, 5-a] quinoline
    Amol Haridas Kategaonkar, Rajkumar U. Pokalwar, Swapnil S. Sonar · 2009 · European Journal of Medicinal Chemistry
  29. Darwin's Warm Little Pond: A One‐Pot Reaction for Prebiotic Phosphorylation and the Mobilization of Phosphate from Minerals in a Urea‐Based Solvent
    Burcar, Bradley, Pasek, Matthew, Gull, Maheen, Cafferty, Brian J., Velasco, Francisco, Hud, Nicholas V., Menor‐Salván, César · 2016 · Angewandte Chemie International Edition
  30. Design of a Synthetic Nuclease: DNA Hydrolysis by a Zinc-Binding Peptide Tethered to a Rhodium Intercalator
    Marilena P. Fitzsimons, Jacqueline K. Barton · 1997 · Journal of the American Chemical Society
  31. Interactions Between Phosphorus, Zinc, and Iron Homeostasis in Nonmycorrhizal and Mycorrhizal Plants
    Xianan Xie, Wentao Hu, Xiaoning Fan, Chen Hui, Ming Tang · 2019 · Frontiers in Plant Science
  32. Potent Mechanism-based Inhibitors for Matrix Metalloproteinases
    Masahiro Ikejiri, M. Margarida Bernardo, R. Daniel Bonfil, Márta Tóth, Mayland Chang, Rafael A. Fridman, Shahriar Mobashery · 2005 · Journal of Biological Chemistry
  33. Isosterism and bioisosterism in drug design
    Alfred Burger · 1991 · Birkhäuser Basel eBooks
  34. The Structural Basis of the Myosin ATPase Activity
    Ivan Rayment · 1996 · Journal of Biological Chemistry
  35. The Compositional and Evolutionary Logic of Metabolism
    Braakman, Rogier, Smith, Eric · 2012 · Physical Biology
  36. Imaging Adenosine Triphosphate (ATP)
    Megha Rajendran, Eric L. Dane, Jason Michael Conley, Mathew Tantama · 2016 · Biological Bulletin
  37. Nucleoside Phosphorylation by Phosphate Minerals
    Giovanna Costanzo, Raffaele Saladino, Claudia Crestini, Fabiana Ciciriello, Ernesto Di Mauro · 2007 · Journal of Biological Chemistry
  38. Formamide Chemistry and the Origin of Informational Polymers
    Raffaele Saladino, Claudia Crestini, Fabiana Ciciriello, Giovanna Costanzo, Ernesto Di Mauro · 2007 · Chemistry & Biodiversity
  39. ATP‐Driven Synthetic Supramolecular Assemblies: From ATP as a Template to Fuel
    Ananya Mishra, Shikha Dhiman, Subi Jacob George · 2020 · Angewandte Chemie International Edition
  40. How long did it take for life to begin and evolve to cyanobacteria?
    Antonio Lazcano, Stanley Lloyd Miller · 1994 · Journal of Molecular Evolution
  41. Phosphorylation on the Early Earth
    Pasek, Matthew A., Gull, Maheen, Herschy, Barry · 2017 · Chemical Geology
  42. Synthesis of DOPO-Based Phosphonamidates and their Thermal Properties
    N. Matthias Neisius, Manuel Lutz, Daniel Rentsch · 2014 · Industrial & Engineering Chemistry Research
  43. Harnessing Conformational Plasticity to Generate Designer Enzymes
    Rory Crean, Jasmine M. Gardner, Shina Caroline Lynn Kamerlin · 2020 · Journal of the American Chemical Society
  44. Exploring the diversity of protein modifications: special bacterial phosphorylation systems
    Ivan Mijakovic̀, Christophe Grangeasse, Kürşad Turgay · 2016 · FEMS Microbiology Reviews
  45. Membrane Transport in Primitive Cells
    Sheref S. Mansy · 2010 · Cold Spring Harbor Perspectives in Biology
  46. Phosphates, DNA, and the Search for Nonterrean Life: A Second Generation Model for Genetic Molecules
    Steven A. Benner, Daniel Hutter · 2002 · Bioorganic Chemistry
  47. Role of p K a of Nucleobases in the Origins of Chemical Evolution
    Ramanarayanan Krishnamurthy · 2012 · Accounts of Chemical Research
  48. (α-Monofluoroalkyl)phosphonates: a class of isoacidic and “tunable” mimics of biological phosphates
    David B. Berkowitz, Mohua Bose · 2001 · Journal of Fluorine Chemistry
  49. Hydrolytic Cleavage of DNA by Ternary Amino Acid Schiff Base Copper( II ) Complexes Having Planar Heterocyclic Ligands
    Pattubala A. N. Reddy, Munirathinam Nethaji, Akhil Ranjan Chakravarty · 2004 · European Journal of Inorganic Chemistry
  50. The prospect of alien life in exotic forms on other worlds
    Schulze-Makuch, Dirk, Irwin, Louis N. · 2006 · Naturwissenschaften
  51. Toward Efficient Zn(II)-Based Artificial Nucleases
    Elisa Boseggia, Maddalena Gatos, Lorena Lucatello · 2004 · Journal of the American Chemical Society
  52. High-resolution nuclear magnetic resonance spectroscopy studies of polysaccharides crosslinked by sodium trimetaphosphate: a proposal for the reaction mechanism
    Stéphane Lack, Virginie Dulong, Luc Picton, Didier Le Cerf, Eric Condamine · 2007 · Carbohydrate Research
  53. Strategies of organic phosphorus recycling by soil bacteria: acquisition, metabolism, and regulation
    Yeonsoo Park, Mina Solhtalab, Wiriya Thongsomboon · 2022 · Environmental Microbiology Reports
  54. A Unidirectional DNA Walker That Moves Autonomously along a Track
    Peng Yin, Hao Yan, Xiaoju G. Daniell, Andrew J. Turberfield, John H. Reif · 2004 · Angewandte Chemie
  55. DNA Binding, Cleavage, and Cytotoxic Activity of the Preorganized Dinuclear Zinc(II) Complex of Triazacyclononane Derivatives
    Xin Sheng, Xun Guo, Xiaomin Lu, Guoyuan Lu, Ying Shao, Fang Liu, Qiang Xu · 2008 · Bioconjugate Chemistry
  56. THE SKELETON SPACE: A FINITE SET OF ORGANIC DESIGNS
    Roger D. K. Thomas, Wolf‐Ernst Reif · 1993 · Evolution
  57. Prebiotic Stereoselective Synthesis of Purine and Noncanonical Pyrimidine Nucleotide from Nucleobases and Phosphorylated Carbohydrates
    Kim, Hyo-Joong, Benner, Steven A. · 2017 · Proceedings of the National Academy of Sciences
  58. Stereospecific Furanosylations Catalyzed by Bis-thiourea Hydrogen-Bond Donors
    Andrew B. Mayfield, Jan B. Metternich, Adam H. Trotta, Eric N. Jacobsen · 2020 · Journal of the American Chemical Society
  59. Molecular Ratchets and Kinetic Asymmetry: Giving Chemistry Direction
    Stefan Borsley, David A. Leigh, Benjamin M. W. Roberts · 2024 · Angewandte Chemie International Edition
  60. Mechanisms and Impact of Symbiotic Phosphate Acquisition
    Chai Hao Chiu, Uta Paszkowski · 2019 · Cold Spring Harbor Perspectives in Biology
  61. On the origin of life in the Zinc world: 1. Photosynthesizing, porous edifices built of hydrothermally precipitated zinc sulfide as cradles of life on Earth
    Armen Y. Mulkidjanian · 2009 · Biology Direct
  62. Phosphate Diester Hydrolysis and DNA Damage Promoted by Newcis-Aqua/Hydroxy Copper(II) Complexes Containing Tridentate Imidazole-rich Ligands
    Marciela Scarpellini, Ademir Neves, Rosmari Hörner et al. · 2003 · Inorganic Chemistry
  63. DNA hydrolytic cleavage catalyzed by synthetic multinuclear metallonucleases
    Changlin Liu, Li Wang · 2008 · Dalton Transactions
  64. The farther, the safer: a manifesto for securely navigating synthetic species away from the old living world
    P. Marlière · 2009 · Journal of Systems and Synthetic Biology
  65. A comprehensive synthesis unveils the mysteries of phosphate‐solubilizing microbes
    Jintian Li, Jing‐li Lu, Hongyu Wang, Zhou Fang, Xiaojuan Wang, Shi‐wei Feng, Zhang Wang, Ting Yuan, Sheng‐chang Zhang, Shu‐ning Ou et al. · 2021 · Biological reviews/Biological reviews of the Cambridge Philosophical Society
  66. Synthesis, DNA‐Binding, Cleavage, and Cytotoxic Activity of New 1,7‐Dioxa‐4,10‐diazacyclododecane Artificial Receptors Containing Bisguanidinoethyl or Diaminoethyl Double Side Arms
    Xin Sheng, Xiaomin Lu, Yueting Chen, Guoyuan Lu, Jingjing Zhang, Ying Shao, Fang Liu, Qiang Xu · 2007 · Chemistry - A European Journal
  67. The X-ray Crystal Structures of Yersinia Tyrosine Phosphatase with Bound Tungstate and Nitrate
    Eric B. Fauman, Chantana Yuvaniyama, Heidi Schubert · 1996 · Journal of Biological Chemistry
  68. Resolving Apparent Conflicts between Theoretical and Experimental Models of Phosphate Monoester Hydrolysis
    Fernanda Duarte, Johan Åqvist, Nicholas H. Williams, Shina Caroline Lynn Kamerlin · 2014 · Journal of the American Chemical Society
  69. Positively Charged Phosphorus as a Hydrogen Bond Acceptor
    Anne S. Hansen, Lin Du, Henrik Grum Kjaergaard · 2014 · The Journal of Physical Chemistry Letters
  70. Mechanistic Studies on Protein Tyrosine Phosphatases
    Zhong‐Yin Zhang · 2003 · Progress in nucleic acid research and molecular biology
  71. Consequences of Replacing the DNA 3‘-Oxygen by an Amino Group: High-Resolution Crystal Structure of a Fully Modified N3‘ → P5‘ Phosphoramidate DNA Dodecamer Duplex
    Valentina A. Tereshko, Sergei M Gryaznov, Martin Egli · 1998 · Journal of the American Chemical Society
  72. Singularities: Landmarks on the Pathways of Life
    de Duve, Christian · 2005
  73. Formamide as the main building block in the origin of nucleic acids
    Giovanna Costanzo, Raffaele Saladino, Claudia Crestini, Fabiana Ciciriello, Ernesto Di Mauro · 2007 · BMC Evolutionary Biology
  74. The role of phosphorus in chemical evolution
    Enrique Maciá · 2005 · Chemical Society Reviews
  75. A synthetic genetic polymer with an uncharged backbone chemistry based on alkyl phosphonate nucleic acids
    Sebastian Arangundy‐Franklin, Alexander I. Taylor, Benjamin T. Porebski, Vito Genna, Sew‐Yeu Peak‐Chew, Alexandra Vaisman, Roger Woodgate, Modesto Orozco, Philipp Holliger · 2019 · Nature Chemistry
  76. Selective Synthesis of 2,3-Disubstituted-2H-isoindol-1-ylphosphonate and 2,3-Disubstituted-1,2-dihydroiso- quinolin-1-ylphosphonate via Metal-Tuned Reaction of α-Amino (2-Alkynylphenyl)methylphosphonate
    Qiuping Ding, Yang Ye, Renhua Fan · 2007 · The Journal of Organic Chemistry
  77. Proton conduction mechanisms in the phosphoric acid–water system (H 4 P 2 O 7 –H 3 PO 4 ·2H 2 O): a 1 H, 31 P and 17 O PFG-NMR and conductivity study
    Jan-Patrick Melchior, Klaus‐Dieter Kreuer, Joachim Maier · 2016 · Physical Chemistry Chemical Physics
  78. THERAPEUTIC OLIGONUCLEOTIDES, IMPURITIES, DEGRADANTS, AND THEIR CHARACTERIZATION BY MASS SPECTROMETRY
    Soheil Pourshahian · 2019 · Mass Spectrometry Reviews
  79. Readily available phosphate from minerals in early aqueous environments on Mars
    C. T. Adcock, Elisabeth M. Hausrath, Paul M. Forster · 2013 · Nature Geoscience
  80. A Fundamental Assumption about OH- Attack in Phosphate Ester Hydrolysis Is Not Fully Justified
    Jan Florián, Arieh Warshel · 1997 · Journal of the American Chemical Society
  81. Archaeal protein kinases and protein phosphatases: insights from genomics and biochemistry
    Peter James Kennelly · 2003 · Biochemical Journal
  82. Rare Earth Metal-Mediated Precision Polymerization of Vinylphosphonates and Conjugated Nitrogen-Containing Vinyl Monomers
    Benedikt S. Soller, Stephan Salzinger, Bernhard Rieger · 2015 · Chemical Reviews
  83. Methane on Mars and Habitability: Challenges and Responses
    Yuk Ling Yung, Pin Chen, Kenneth H. Nealson, S. K. Atreya, Patrick Beckett, Jennifer G. Blank, Bethany L. Ehlmann, John M. Eiler, Giuseppe Etiope, James Gregory Ferry et al. · 2018 · Astrobiology
  84. Direct evidence for the availability of reactive, water soluble phosphorus on the early Earth. H-Phosphinic acid from the Nantan meteorite
    David E. Bryant, Terence P. Kee · 2006 · Chemical Communications
  85. Structure−Reactivity Studies in Copper(II)-Catalyzed Phosphodiester Hydrolysis
    Eric L. Hegg, S.H. Mortimore, Chin Li Cheung, Jennifer E. Huyett, Douglas R. Powell, Judith N. Burstyn · 1999 · Inorganic Chemistry
  86. Green Rust: The Simple Organizing ‘Seed’ of All Life?
    Russell, Michael J. · 2018 · Life
  87. Phosphorus availability on the early Earth and the impacts of life
    Craig Robert Walton, Sophia D. Ewens, John D. Coates, Ruth Elaine Blake, Noah J. Planavsky, Christopher T. Reinhard, Pengcheng Ju, Jihua Hao, Matthew A. Pasek · 2023 · Nature Geoscience
  88. An Asymmetric Dizinc Phosphodiesterase Model with Phenolate and Carboxylate Bridges
    Jingwen Chen, Xiaoyong Wang, Yangguang Zhu · 2005 · Inorganic Chemistry
  89. Description of Phosphate Hydrolysis Reactions with the Self-Consistent-Charge Density-Functional-Tight-Binding (SCC-DFTB) Theory. 1. Parameterization
    Yang Yang, Haibo B. Yu, Darrin M. York · 2008 · Journal of Chemical Theory and Computation
  90. Primitive Genetic Polymers
    Engelhart, A. E., Hud, N. V. · 2010 · Cold Spring Harbor Perspectives in Biology
  91. Serine-Selective Bioconjugation
    Julien C. Vantourout, Srinivasa Rao Adusumalli, Kyle W. Knouse, Dillon T. Flood, Antonio Ramı́rez, Natalia M. Padial, Alena Istrate, Katarzyna Maziarz, Justine N. deGruyter, Rohan R. Merchant et al. · 2020 · Journal of the American Chemical Society
  92. The catalytic subunit of cAMP-dependent protein kinase: prototype for an extended network of communication
    Christopher Michael Smith, Elzbieta Radzio-Andzelm, Madhusudan, Pearl Akamine, Susan Serota Taylor · 1999 · Progress in Biophysics and Molecular Biology
  93. Singularities: landmarks on the pathways of life
    2006 · Choice Reviews Online
  94. A Chemist’s Perspective on the Role of Phosphorus at the Origins of Life
    Christian Fernández‐García, Adam J. Coggins, Matthew W. Powner · 2017 · Life
  95. Calcium Signaling and Gene Expression
    Basant K. Puri · 2019 · Advances in experimental medicine and biology
  96. Nature‐Inspired Environmental “Phosphorylation” Boosts Photocatalytic H 2 Production over Carbon Nitride Nanosheets under Visible‐Light Irradiation
    Guigao Liu, Tao Wang, Huabin Zhang, Xianguang Meng, Dong Hao, Kun Chang, Peng Li, Tetsuya Kako, Jinhua Ye · 2015 · Angewandte Chemie
  97. Briefly Bound to Activate: Transient Binding of a Second Catalytic Magnesium Activates the Structure and Dynamics of CDK2 Kinase for Catalysis
    Zhao Bao, Douglas M. Jacobsen, Matthew Adam Young · 2011 · Structure
  98. DNA Hydrolytic Cleavage by the Diiron(III) Complex Fe2(DTPB)(μ-O)(μ-Ac)Cl(BF4)2: Comparison with Other Binuclear Transition Metal Complexes
    Changlin Liu, Siwang Yu, Dongfeng Li · 2002 · Inorganic Chemistry
  99. Walden-Inversion-Enforced Transition-State Stabilization in a Protein Tyrosine Phosphatase
    Cristóbal Alhambra, Li Wu, Zhong‐Yin Zhang, Jiali Gao · 1998 · Journal of the American Chemical Society
  100. Thermodynamics of Prebiotic Phosphorylation
    Matthew A. Pasek · 2019 · Chemical Reviews