The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
The Chemistry of Self-Splicing RNA and RNA Enzymes
Abstract
Proteins are not the only catalysts of cellular reactions; there is a growing list of RNA molecules that catalyze RNA cleavage and joining reactions. The chemical mechanisms of RNA-catalyzed reactions are discussed with emphasis on the self-splicing ribosomal RNA precursor of Tetrahymena and the enzymatic activities of its intervening sequence RNA. Wherever appropriate, catalysis by RNA is compared to catalysis by protein enzymes.
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Citations
Cites
Gilbert, W. (1986) · Nature · doi:10.1038/319618a0 · Cited by 2,721
The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme
Guerrier-Takada, C., Gardiner, K., Marsh, T., Pace, N., & Altman, S. (1983) · Cell · doi:10.1016/0092-8674(83)90117-4 · Cited by 2,684
Cited by
Self‐Assembly in Natural and Unnatural Systems
Philp, D., & Stoddart, J. F. (1996) · Angewandte Chemie International Edition in English · doi:10.1002/anie.199611541 · Cited by 2,115
A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis
Greider, C. W., & Blackburn, E. H. (1989) · Nature · doi:10.1038/337331a0 · Cited by 1,643
A general two-metal-ion mechanism for catalytic RNA
Steitz, T. A., & Steitz, J. A. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.14.6498 · Cited by 1,171
RNA evolution and the origins of life
Joyce, G. F. (1989) · Nature · doi:10.1038/338217a0 · Cited by 658
Directed Evolution of Nucleic Acid Enzymes
Joyce, G. F. (2004) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.73.011303.073717 · Cited by 515
Metadata
- Authors
- Cech, T. R.
- Venue
- Science
- Published
- 1987-06-19
- Volume
- 236
- Issue
- 4808
- Pages
- 1532-1539
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2062911181
- Cited by
- 531
- References
- 2
- FWCI
- 14.93
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
