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Primary Structure of the β Subunit of the DHP-Sensitive Calcium Channel from Skeletal Muscle
Open accessAbstract
Complementary DNAs for the β subunit of the dihydropyridine-sensitive calcium channel of rabbit skeletal muscle were isolated on the basis of peptide sequences derived from the purified protein. The deduced primary structure is without homology to other known protein sequences and is consistent with the β subunit being a peripheral membrane protein associated with the cytoplasmic aspect of the sarcolemma. The protein contains sites that might be expected to be preferentially phosphorylated by protein kinase C and guanosine 3′,5′-monophosphate-dependent protein kinase. A messenger RNA for this protein appears to be expressed in brain.
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Citations
Cited by
Structure and Regulation of Voltage-Gated Ca 2+ Channels
Catterall, W. A. (2000) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.16.1.521 · Cited by 2,344
Voltage-Gated Calcium Channels
Catterall, W. A. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a003947 · Cited by 1,628
Primary structure and functional expression from complementary DNA of a brain calcium channel
Mori, Y., Friedrich, T., Kim, M.-S., Mikami, A., Nakai, J., Ruth, P., Bosse, E., Hofmann, F., Flockerzi, V., Furuichi, T., et al. (1991) · Nature · doi:10.1038/350398a0 · Cited by 866
Self-citationHell, J. W., Westenbroek, R. E., Warner, C., Ahlijanian, M. K., Prystay, W., Gilbert, M. M., Snutch, T. P., & Catterall, W. A. (1993) · The Journal of cell biology · doi:10.1083/jcb.123.4.949 · Cited by 759
Voltage-gated ion channels and gating modifier toxins
Catterall, W. A., Cestèle, S., Yarov-Yarovoy, V., Yu, F. H., Konoki, K., & Scheuer, T. (2007) · Toxicon · doi:10.1016/j.toxicon.2006.09.022 · Cited by 640
Metadata
- Authors
- Ruth, P., Röhrkasten, A., Biel, M., Bosse, E., Regulla, S., Meyer, H. E., Flockerzi, V., & Hofmann, F.
- Venue
- Science
- Published
- 1989-09-08
- Volume
- 245
- Issue
- 4922
- Pages
- 1115-1118
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2056622362
- Cited by
- 374
- References
- 0
- FWCI
- 10.17
- Type
- journal article
- Language
- en
- Open access
- green
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- Ruth, P., Röhrkasten, A., Biel, M., Bosse, E., Regulla, S., Meyer, H. E., Flockerzi, V., & Hofmann, F. (1989). Primary Structure of the β Subunit of the DHP-Sensitive Calcium Channel from Skeletal Muscle. Science. https://doi.org/10.1126/science.2549640
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
