The DOI matches its Crossref record; 134 of the 134 references it cites were found in a registry or an index.
Morphogenesis of the Polarized Epithelial Cell Phenotype
Abstract
Polarized epithelial cells play fundamental roles in the ontogeny and function of a variety of tissues and organs in mammals. The morphogenesis of a sheet of polarized epithelial cells (the trophectoderm) is the first overt sign of cellular differentiation in early embryonic development. In the adult, polarized epithelial cells line all body cavities and occur in tissues that carry out specialized vectorial transport functions of absorption and secretion. The generation of this phenotype is a multistage process requiring extracellular cues and the reorganization of proteins in the cytoplasm and on the plasma membrane; once established, the phenotype is maintained by the segregation and retention of specific proteins and lipids in distinct apical and basal-lateral plasma membrane domains.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
JUNCTIONAL COMPLEXES IN VARIOUS EPITHELIA
Farquhar, M. G., & Palade, G. E. (1963) · The Journal of Cell Biology · doi:10.1083/jcb.17.2.375 · Cited by 3,635
Intracellular Aspects of the Process of Protein Synthesis
Palade, G. (1975) · Science · doi:10.1126/science.1096303 · Cited by 3,564
The cadherins: cell-cell adhesion molecules controlling animal morphogenesis
Takeichi, M. (1988) · Development · doi:10.1242/dev.102.4.639 · Cited by 1,615
Wessells, N. K., Spooner, B. S., Ash, J. F., Bradley, M. O., Luduena, M. A., Taylor, E. L., Wrenn, J. T., & Yamada, K. M. (1971) · Science · doi:10.1126/science.171.3967.135 · Cited by 1,553
CELL-SURFACE ANCHORING OF PROTEINS VIA GLYCOSYL-PHOSPHATIDYLINOSITOL STRUCTURES
Ferguson, M. A. J., & Williams, A. F. (1988) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.57.070188.001441 · Cited by 1,279
The trans Golgi Network: Sorting at the Exit Site of the Golgi Complex
Griffiths, G., & Simons, K. (1986) · Science · doi:10.1126/science.2945253 · Cited by 1,185
Pathways of Protein Secretion in Eukaryotes
Kelly, R. B. (1985) · Science · doi:10.1126/science.2994224 · Cited by 1,052
Constitutive and Regulated Secretion of Proteins
Burgess, T. L., & Kelly, R. B. (1987) · Annual Review of Cell Biology · doi:10.1146/annurev.cb.03.110187.001331 · Cited by 1,017
Structural and Functional Roles of Glycosyl-Phosphatidylinositol in Membranes
Low, M. G., & Saltiel, A. R. (1988) · Science · doi:10.1126/science.3276003 · Cited by 952
Cell Surface Polarity in Epithelia
Simons, K., & Fuller, S. D. (1985) · Annual Review of Cell Biology · doi:10.1146/annurev.cb.01.110185.001331 · Cited by 876
Cited by
Functional rafts in cell membranes
Simons, K., & Ikonen, E. (1997) · Nature · doi:10.1038/42408 · Cited by 9,757
Brown, D. A., & Rose, J. K. (1992) · Cell · doi:10.1016/0092-8674(92)90189-j · Cited by 2,921
Complex Phenotype of Mice Lacking Occludin, a Component of Tight Junction Strands
Saitou, M., Furuse, M., Sasaki, H., Schulzke, J.-D., Fromm, M., Takano, H., Noda, T., & Tsukita, S. (2000) · Molecular Biology of the Cell · doi:10.1091/mbc.11.12.4131 · Cited by 1,195
Ikenouchi, J., Matsuda, M., Furuse, M., & Tsukita, S. (2003) · Journal of Cell Science · doi:10.1242/jcs.00389 · Cited by 678
Itoh, M., Nagafuchi, A., Moroi, S., & Tsukita, S. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.138.1.181 · Cited by 677
Metadata
- Authors
- Rodriguez-Boulan, E., & Nelson, W. J.
- Venue
- Science
- Published
- 1989-08-18
- Volume
- 245
- Issue
- 4919
- Pages
- 718-725
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1976094538
- Cited by
- 1,085
- References
- 134
- FWCI
- 30.00
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Morphogenesis of the Polarized Epithelial Cell Phenotype. https://app.cochat.ai/papers/10.1126/science.2672330
- The paper
- Rodriguez-Boulan, E., & Nelson, W. J. (1989). Morphogenesis of the Polarized Epithelial Cell Phenotype. Science. https://doi.org/10.1126/science.2672330
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
