The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
T Cell Awareness of Paternal Alloantigens During Pregnancy
Abstract
During pregnancy a semiallogeneic fetus survives despite the presence of maternal T cells specific for paternally inherited histocompatibility antigens. A mouse transgenic for a T cell receptor recognizing the major histocompatibility (MHC) antigen H-2K b was used to follow the fate of T cells reactive to paternal alloantigens. In contrast to syngeneic and third-party allogeneic pregnancies, mice bearing a K b -positive conceptus had reduced numbers of K b -reactive T cells and accepted K b -positive tumor grafts. T cell phenotype and responsiveness were restored after delivery. Thus, during pregnancy maternal T cells acquire a transient state of tolerance specific for paternal alloantigens.
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Citations
Cites
Wegmann, T. G., Lin, H., Guilbert, L., & Mosmann, T. R. (1993) · Immunology Today · doi:10.1016/0167-5699(93)90235-d · Cited by 2,852
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Nelson, J. L., Furst, D. E., Maloney, S., Gooley, T., Evans, P. C., Smith, A., Bean, M. A., Ober, C., & Bianchi, D. W. (1998) · The Lancet · doi:10.1016/s0140-6736(97)08357-8 · Cited by 601
Gale, E. A. M., & Gillespie, K. M. (2001) · Diabetologia · doi:10.1007/s001250051573 · Cited by 558
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Harbo, H. F., Gold, R., & Tintoré, M. (2013) · Therapeutic Advances in Neurological Disorders · doi:10.1177/1756285613488434 · Cited by 529
The role of the immune system in preeclampsia
Saito, S., Shiozaki, A., Nakashima, A., Sakai, M., & Sasaki, Y. (2007) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2007.02.006 · Cited by 351
Metadata
- Authors
- Tafuri, A., Alferink, J., Möller, P., Hämmerling, G. J., & Arnold, B.
- Venue
- Science
- Published
- 1995-10-27
- Volume
- 270
- Issue
- 5236
- Pages
- 630-633
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1989496524
- Cited by
- 572
- References
- 1
- FWCI
- 8.73
- Type
- journal article
- Language
- en
- Open access
- closed
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- Tafuri, A., Alferink, J., Möller, P., Hämmerling, G. J., & Arnold, B. (1995). T Cell Awareness of Paternal Alloantigens During Pregnancy. Science. https://doi.org/10.1126/science.270.5236.630
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
