The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Transition in Specification of Embryonic Metazoan DNA Replication Origins
Abstract
In early Xenopus embryos, in which ribosomal RNA genes (rDNA) are not transcribed, rDNA replication initiates and terminates at 9- to 12-kilobase pair intervals, with no detectable dependence on specific DNA sequences. Resumption of ribosomal RNA (rRNA) synthesis at late blastula and early gastrula is accompanied by a specific repression of replication initiation within transcription units; the frequency of initiation within intergenic spacers remains as high as in early blastula. These results demonstrate that for rRNA genes, circumscribed zones of replication initiation emerge in intergenic DNA during the time in metazoan development when the chromatin is remodeled to allow gene transcription.
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Citations
Cites
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A replication fork barrier at the 3′ end of yeast ribosomal RNA genes
Brewer, B. J., & Fangman, W. L. (1988) · Cell · doi:10.1016/0092-8674(88)90222-x · Cited by 534
Organization of replication of ribosomal DNA in Saccharomyces cerevisiae.
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Replication structure of the human & beta;-globin gene domain
Kitsberg, D., Selig, S., Keshet, I., & Cedar, H. (1993) · Nature · doi:10.1038/366588a0 · Cited by 275
Identification of an origin of bidirectional DNA replication in mammalian chromosomes
Burhans, W. C., Vassilev, L. T., Caddle, M. S., Heintz, N. H., & DePamphills, M. L. (1990) · Cell · doi:10.1016/0092-8674(90)90270-o · Cited by 267
Initiation and termination of DNA replication in human rRNA genes.
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Review Lecture - Replication of DNA in the chromosomes of eukaryotes
Callan, H. G. (1972) · Proceedings of the Royal Society of London. Series B. Biological Sciences · doi:10.1098/rspb.1972.0039 · Cited by 242
rRNA synthesis in the nucleolus
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Characterization of three sites of RNA 3$prime; end formation in the Xenopus ribosomal gene spacer
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Cited by
Cell cycle control of DNA replication
Stillman, B. (1996) · Science · doi:10.1126/science.274.5293.1659 · Cited by 507
Replication landscape of the human genome
Petryk, N., Kahli, M., d'Aubenton-Carafa, Y., Jaszczyszyn, Y., Shen, Y., Silvain, M., Thermes, C., Chen, C.-L., & Hyrien, O. (2016) · Nature Communications · doi:10.1038/ncomms10208 · Cited by 355
Self-citationThe origin recognition complex: from simple origins to complex functions
Bell, S. P. (2002) · Genes & Development · doi:10.1101/gad.969602 · Cited by 288
DNA replication as a target of the DNA damage checkpoint
Zegerman, P., & Diffley, J. F. X. (2009) · DNA Repair · doi:10.1016/j.dnarep.2009.04.023 · Cited by 128
Metadata
- Authors
- Hyrien, O., Maric, C., & Méchali, M.
- Venue
- Science
- Published
- 1995-11-10
- Volume
- 270
- Issue
- 5238
- Pages
- 994-997
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2085666970
- Cited by
- 323
- References
- 19
- FWCI
- 4.97
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
