The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Phosphoinositides as Regulators in Membrane Traffic
Abstract
Phosphorylated products of phosphatidylinositol play critical roles in the regulation of membrane traffic, in addition to their classical roles as second messengers in signal transduction at the cell surface. Growing evidence suggests that phosphorylation-dephosphorylation of the polar heads of phosphoinositides (polyphosphorylated inositol lipids) in specific intracellular locations signals either the recruitment or the activation of proteins essential for vesicular transport. Cross talk between phosphatidylinositol metabolites and guanosine triphosphatases is an important feature of these regulatory mechanisms.
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Cites
Inositol trisphosphate and calcium signalling
Berridge, M. J. (1993) · Nature · doi:10.1038/361315a0 · Cited by 6,545
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Lipton, P. (1999) · Physiological Reviews · doi:10.1152/physrev.1999.79.4.1431 · Cited by 3,043
Mechanisms of phagocytosis in macrophages
Aderem, A., & Underhill, D. M. (1999) · Annual Review of Immunology · doi:10.1146/annurev.immunol.17.1.593 · Cited by 2,854
EEA1 links PI(3)K function to Rab5 regulation of endosome fusion
Simonsen, A., Lippe, R., Christoforidis, S., Gaullier, J.-M., Brech, A., Callaghan, J., Toh, B.-H., Murphy, C., Zerial, M., & Stenmark, H. (1998) · Nature · doi:10.1038/28879 · Cited by 1,133
Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling
SHEPHERD, P. R., WITHERS, D. J., & SIDDLE, K. (1998) · Biochemical Journal · doi:10.1042/bj3330471 · Cited by 953
Araki, N., Johnson, M. T., & Swanson, J. A. (1996) · The Journal of cell biology · doi:10.1083/jcb.135.5.1249 · Cited by 949
“It phosphorylates phosphoinositides at the D3 hydroxyl of inositol, producing phosphatidylinositol 3-phosphate, phosphatidylinositol (3, 4)-bisphosphate, or phosphatidylinositol (3, 4, 5)-trisphosphate (11).”
Background
Metadata
- Authors
- De Camilli, P., Emr, S. D., McPherson, P. S., & Novick, P.
- Venue
- Science
- Published
- 1996-03-15
- Volume
- 271
- Issue
- 5255
- Pages
- 1533-1539
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2080037386
- Cited by
- 710
- References
- 1
- FWCI
- 37.87
- Type
- journal article
- Language
- en
- Open access
- closed
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- The paper
- De Camilli, P., Emr, S. D., McPherson, P. S., & Novick, P. (1996). Phosphoinositides as Regulators in Membrane Traffic. Science. https://doi.org/10.1126/science.271.5255.1533
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
