The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
Selective Activation of NF-κB by Nerve Growth Factor Through the Neurotrophin Receptor p75
Abstract
Nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and neurotrophin-3 (NT-3) selectively bind to distinct members of the Trk family of tyrosine kinase receptors, but all three bind with similar affinities to the neurotrophin receptor p75 (p75 NTR ). The biological significance of neurotrophin binding to p75 NTR in cells that also express Trk receptors has been difficult to ascertain. In the absence of TrkA, NGF binding to p75 NTR activated the transcription factor nuclear factor kappa B (NF-κB) in rat Schwann cells. This activation was not observed in Schwann cells isolated from mice that lacked p75 NTR . The effect was selective for NGF; NF-κB was not activated by BDNF or NT-3.
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Cites
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
Chomczynski, P., & Sacchi, N. (1987) · Analytical Biochemistry · doi:10.1016/0003-2697(87)90021-2 · Cited by 46,426
Function and Activation of NF-kappaB in the Immune System
Baeuerle, P. A., & Henkel, T. (1994) · Annual Review of Immunology · doi:10.1146/annurev.iy.12.040194.001041 · Cited by 4,745
Self-citationA novel domain within the 55 kd TNF receptor signals cell death
Tartaglia, L. A., Ayres, T. M., Wong, G. H. W., & Goeddel, D. V. (1993) · Cell · doi:10.1016/0092-8674(93)90464-2 · Cited by 1,288
The Trk family of neurotrophin receptors
Barbacid, M. (1994) · Journal of Neurobiology · doi:10.1002/neu.480251107 · Cited by 1,281
Hempstead, B. L., Martin-Zanca, D., Kaplan, D. R., Parada, L. F., & Chao, M. V. (1991) · Nature · doi:10.1038/350678a0 · Cited by 1,229
Tartaglia, L. A., & Goeddel, D. V. (1992) · Immunology Today · doi:10.1016/0167-5699(92)90116-o · Cited by 1,035
Lee, K.-F., Li, E., Huber, L. J., Landis, S. C., Sharpe, A. H., Chao, M. V., & Jaenisch, R. (1992) · Cell · doi:10.1016/0092-8674(92)90286-l · Cited by 956
Gene transfer and molecular cloning of the rat nerve growth factor receptor
Radeke, M. J., Misko, T. P., Hsu, C., Herzenberg, L. A., & Shooter, E. M. (1987) · Nature · doi:10.1038/325593a0 · Cited by 938
Binding of brain-derived neurotrophic factor to the nerve growth factor receptor
Rodriguez-Tebar, A., Dechant, G., & Barde, Y.-A. (1990) · Neuron · doi:10.1016/0896-6273(90)90107-q · Cited by 710
Self-citationHeumann, R., Lindholm, D., Bandtlow, C., Meyer, M., Radeke, M. J., Misko, T. P., Shooter, E., & Thoenen, H. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.23.8735 · Cited by 701
Cited by
Neurotrophins: Roles in Neuronal Development and Function
Huang, E. J., & Reichardt, L. F. (2001) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.24.1.677 · Cited by 4,394
Activators and target genes of Rel/NF-κB transcription factors
Pahl, H. L. (1999) · Oncogene · doi:10.1038/sj.onc.1203239 · Cited by 3,727
Neurotrophin signal transduction in the nervous system
Kaplan, D. R., & Miller, F. D. (2000) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(00)00092-1 · Cited by 1,944
Nerve Growth Factor Signaling, Neuroprotection, and Neural Repair
Sofroniew, M. V., Howe, C. L., & Mobley, W. C. (2001) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.24.1.1217 · Cited by 1,284
NF-kB: a crucial transcription factor for glial and neuronal cell function
O'Neill, L. A. J., & Kaltschmidt, C. (1997) · Trends in Neurosciences · doi:10.1016/s0166-2236(96)01035-1 · Cited by 1,013
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Metadata
- Authors
- Carter, B. D., Kaltschmidt, C., Kaltschmidt, B., Offenhäuser, N., Böhm-Matthaei, R., Baeuerle, P. A., & Barde, Y.-A.
- Venue
- Science
- Published
- 1996-04-26
- Volume
- 272
- Issue
- 5261
- Pages
- 542-545
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2081555648
- Cited by
- 658
- References
- 35
- FWCI
- 30.27
- Type
- journal article
- Language
- en
- Open access
- closed
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- Carter, B. D., Kaltschmidt, C., Kaltschmidt, B., Offenhäuser, N., Böhm-Matthaei, R., Baeuerle, P. A., & Barde, Y.-A. (1996). Selective Activation of NF-κB by Nerve Growth Factor Through the Neurotrophin Receptor p75. Science. https://doi.org/10.1126/science.272.5261.542
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
