The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Molecular Genetics of Human Blood Pressure Variation
Abstract
Hypertension is a common multifactorial vascular disorder of largely unknown cause. Recognition that hypertension is in part genetically determined has motivated studies to identify mutations that confer susceptibility. Thus far, mutations in at least 10 genes have been shown to alter blood pressure; most of these are rare mutations imparting large quantitative effects that either raise or lower blood pressure. These mutations alter blood pressure through a common pathway, changing salt and water reabsorption in the kidney. These findings demonstrate the utility of molecular genetic approaches to the understanding of blood pressure variation and may provide insight into the physiologic mechanisms underlying common forms of hypertension.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A genome-wide search for human type 1 diabetes susceptibility genes
Davies, J. L., Kawaguchi, Y., Bennett, S. T., Copeman, J. B., Cordell, H. J., Pritchard, L. E., Reed, P. W., Gough, S. C. L., Jenkins, S. C., Palmer, S. M., et al. (1994) · Nature · doi:10.1038/371130a0 · Cited by 1,276
Lifton, R. P., Dluhy, R. G., Powers, M., Rich, G. M., Cook, S., Ulick, S., & Lalouel, J.-M. (1992) · Nature · doi:10.1038/355262a0 · Cited by 1,158
Self-citationChang, S. S., Grunder, S., Hanukoglu, A., Rösler, A., Mathew, P. M., Hanukoglu, I., Schild, L., Lu, Y., Shimkets, R. A., Nelson-Williams, C., et al. (1996) · Nature Genetics · doi:10.1038/ng0396-248 · Cited by 808
Self-citationLinkage disequilibrium mapping in isolated founder populations: diastrophic dysplasia in Finland
Hästbacka, J., de la Chapelle, A., Kaitila, I., Sistonen, P., Weaver, A., & Lander, E. (1992) · Nature Genetics · doi:10.1038/ng1192-204 · Cited by 558
Karl, M., Lamberts, S. W., Detera-Wadleigh, S. D., Encio, I. J., Stratakis, C. A., Hurley, D. M., Accili, D., & Chrousos, G. P. (1993) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.76.3.8445027 · Cited by 241
Cloning and expression of a cDNA for human cytochrome P-450aldo as related to primary aldosteronism
Kawamoto, T., Mitsuuchi, Y., Ohnishi, T., Ichikawa, Y., Yokoyama, Y., Sumimoto, H., Toda, K., Miyahara, K., Kuribayashi, I., Nakao, K., et al. (1990) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(05)81058-7 · Cited by 152
Disorders of steroid 17α-hydroxylase deficiency
Kater, C. E., & Biglieri, E. G. (1994) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(18)30101-4 · Cited by 146
Ogishima, T., Shibata, H., Shimada, H., Mitani, F., Suzuki, H., Saruta, T., & Ishimura, Y. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)99077-0 · Cited by 141
Cited by
Molecular Mechanisms of Human Hypertension
Lifton, R. P., Gharavi, A. G., & Geller, D. S. (2001) · Cell · doi:10.1016/s0092-8674(01)00241-0 · Cited by 1,686
Self-citationHe, F. J., Li, J., & MacGregor, G. A. (2013) · BMJ · doi:10.1136/bmj.f1325 · Cited by 1,358
He, F. J., & MacGregor, G. A. (2009) · Journal of Human Hypertension · doi:10.1038/jhh.2008.144 · Cited by 1,123
He, F. J., & MacGregor, G. A. (2002) · Journal of Human Hypertension · doi:10.1038/sj.jhh.1001459 · Cited by 810
Mechanisms of sodium pump regulation
Therien, A. G., & Blostein, R. (2000) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.2000.279.3.c541 · Cited by 765
Metadata
- Authors
- Lifton, R. P.
- Venue
- Science
- Published
- 1996-05-03
- Volume
- 272
- Issue
- 5262
- Pages
- 676-680
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2033210506
- Cited by
- 629
- References
- 8
- FWCI
- 37.59
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Molecular Genetics of Human Blood Pressure Variation. https://app.cochat.ai/papers/10.1126/science.272.5262.676
- The paper
- Lifton, R. P. (1996). Molecular Genetics of Human Blood Pressure Variation. Science. https://doi.org/10.1126/science.272.5262.676
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
