The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Amino Acid Racemization and the Preservation of Ancient DNA
Abstract
The extent of racemization of aspartic acid, alanine, and leucine provides criteria for assessing whether ancient tissue samples contain endogenous DNA. In samples in which the D/L ratio of aspartic acid exceeds 0.08, ancient DNA sequences could not be retrieved. Paleontological finds from which DNA sequences purportedly millions of years old have been reported show extensive racemization, and the amino acids present are mainly contaminates. An exception is the amino acids in some insects preserved in amber.
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Citations
Cites
Instability and decay of the primary structure of DNA
Lindahl, T. (1993) · Nature · doi:10.1038/362709a0 · Cited by 5,679
Bada, J. L. (1985) · Chemistry and Biochemistry of the Amino Acids · doi:10.1007/978-94-009-4832-7_13 · Cited by 86
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Cited by
Genetic analyses from ancient DNA
Pääbo, S., Poinar, H., Serre, D., Jaenicke-Després, V., Hebler, J., Rohland, N., Kuch, M., Krause, J., Vigilant, L., & Hofreiter, M. (2004) · Annual Review of Genetics · doi:10.1146/annurev.genet.37.110801.143214 · Cited by 1,333
Self-citationHofreiter, M., Serre, D., Poinar, H. N., Kuch, M., & Pääbo, S. (2001) · Nature Reviews Genetics · doi:10.1038/35072071 · Cited by 781
Self-citationAnalysis of one million base pairs of Neanderthal DNA
Green, R. E., Krause, J., Ptak, S. E., Briggs, A. W., Ronan, M. T., Simons, J. F., Du, L., Egholm, M., Rothberg, J. M., Paunovic, M., et al. (2006) · Nature · doi:10.1038/nature05336 · Cited by 760
Self-citationWillerslev, E., & Cooper, A. (2005) · Proceedings of the Royal Society B: Biological Sciences · doi:10.1098/rspb.2004.2813 · Cited by 712
Hofreiter, M. (2001) · Nucleic Acids Research · doi:10.1093/nar/29.23.4793 · Cited by 684
Metadata
- Authors
- Poinar, H. N., Höss, M., Bada, J. L., & Pääbo, S.
- Venue
- Science
- Published
- 1996-05-10
- Volume
- 272
- Issue
- 5263
- Pages
- 864-866
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1965541769
- Cited by
- 391
- References
- 2
- FWCI
- 10.63
- Type
- journal article
- Language
- en
- Open access
- closed
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- Poinar, H. N., Höss, M., Bada, J. L., & Pääbo, S. (1996). Amino Acid Racemization and the Preservation of Ancient DNA. Science. https://doi.org/10.1126/science.272.5263.864
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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