The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Kap104p: A Karyopherin Involved in the Nuclear Transport of Messenger RNA Binding Proteins
Abstract
A cytosolic yeast karyopherin, Kap104p, was isolated and shown to function in the nuclear import of a specific class of proteins. The protein bound directly to repeat-containing nucleoporins and to a cytosolic pool of two nuclear messenger RNA (mRNA) binding proteins, Nab2p and Nab4p. Depletion of Kap104p resulted in a rapid shift of Nab2p from the nucleus to the cytoplasm without affecting the localization of other nuclear proteins tested. This finding suggests that the major function of Kap104p lies in returning mRNA binding proteins to the nucleus after mRNA export.
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Citations
Cites
Distinct functions for the two importin subunits in nuclear protein import
Görlich, D., Vogel, F., Mills, A. D., Hartmann, E., & Laskey, R. A. (1995) · Nature · doi:10.1038/377246a0 · Cited by 474
Cited by
CRM1 Is an Export Receptor for Leucine-Rich Nuclear Export Signals
Fornerod, M., Ohno, M., Yoshida, M., & Mattaj, I. W. (1997) · Cell · doi:10.1016/s0092-8674(00)80371-2 · Cited by 2,081
Nucleocytoplasmic transport: the soluble phase
Mattaj, I. W., & Englmeier, L. (1998) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.67.1.265 · Cited by 1,175
Transport into and out of the Nucleus
Macara, I. G. (2001) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.65.4.570-594.2001 · Cited by 905
Evidence for a Role of CRM1 in Signal-Mediated Nuclear Protein Export
Ossareh-Nazari, B., Bachelerie, F., & Dargemont, C. (1997) · Science · doi:10.1126/science.278.5335.141 · Cited by 717
Neville, M., Stutz, F., Lee, L., Davis, L. I., & Rosbash, M. (1997) · Current Biology · doi:10.1016/s0960-9822(06)00335-6 · Cited by 439
Metadata
- Authors
- Aitchison, J. D., Blobel, G., & Rout, M. P.
- Venue
- Science
- Published
- 1996-10-25
- Volume
- 274
- Issue
- 5287
- Pages
- 624-627
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1997160430
- Cited by
- 303
- References
- 1
- FWCI
- 15.09
- Type
- journal article
- Language
- en
- Open access
- closed
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- Aitchison, J. D., Blobel, G., & Rout, M. P. (1996). Kap104p: A Karyopherin Involved in the Nuclear Transport of Messenger RNA Binding Proteins. Science. https://doi.org/10.1126/science.274.5287.624
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
