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A Similarity Between Viral Defense and Gene Silencing in Plants
Abstract
Gene silencing in plants, in which an endogenous gene is suppressed by introduction of a related transgene, has been used for crop improvement. Observations that viruses are potentially both initiators and targets of gene silencing suggested that this phenomenon may be related to natural defense against viruses. Supporting this idea, it was found that nepovirus infection of nontransgenic plants induces a resistance mechanism that is similar to transgene-induced gene silencing.
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Cited by
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Fire, A., Xu, S., Montgomery, M. K., Kostas, S. A., Driver, S. E., & Mello, C. C. (1998) · Nature · doi:10.1038/35888 · Cited by 15,429
Agrobacterium -Mediated Plant Transformation: the Biology behind the “Gene-Jockeying” Tool
Gelvin, S. B. (2003) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.67.1.16-37.2003 · Cited by 1,379
siRNA-directed inhibition of HIV-1 infection
Novina, C. D., Murray, M. F., Dykxhoorn, D. M., Beresford, P. J., Riess, J., Lee, S.-K., Collman, R. G., Lieberman, J., Shankar, P., & Sharp, P. A. (2002) · Nature Medicine · doi:10.1038/nm725 · Cited by 773
Transposable Elements, Epigenetics, and Genome Evolution
Fedoroff, N. V. (2012) · Science · doi:10.1126/science.338.6108.758 · Cited by 634
An Overview of Some Biopesticides and Their Importance in Plant Protection for Commercial Acceptance
Kumar, J., Ramlal, A., Mallick, D., & Mishra, V. (2021) · Plants · doi:10.3390/plants10061185 · Cited by 474
Metadata
- Authors
- Ratcliff, F., Harrison, B. D., & Baulcombe, D. C.
- Venue
- Science
- Published
- 1997-06-06
- Volume
- 276
- Issue
- 5318
- Pages
- 1558-1560
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2034831897
- Cited by
- 838
- References
- 0
- FWCI
- 61.30
- Type
- journal article
- Language
- en
- Open access
- closed
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- Ratcliff, F., Harrison, B. D., & Baulcombe, D. C. (1997). A Similarity Between Viral Defense and Gene Silencing in Plants. Science. https://doi.org/10.1126/science.276.5318.1558
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
