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Yeast as a Model Organism
Open accessAbstract
Yeast have many genes with homologs in humans. Has our understanding of these genes helped our understanding of human biology or disease? In his Perspective, Botstein argues yes and, as an example, discusses a report in this week9s issue by Sinclair et al. on the yeast homolog of the gene whose dysfunction causes a disease of premature aging, Werner syndrome.
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Citations
Cited by
SGD: Saccharomyces Genome Database
Cherry, J. (1998) · Nucleic Acids Research · doi:10.1093/nar/26.1.73 · Cited by 1,159
Genome-Scale Reconstruction of the Saccharomyces cerevisiae Metabolic Network
Förster, J., Famili, I., Fu, P., Palsson, B. Ø., & Nielsen, J. (2003) · Genome Research · doi:10.1101/gr.234503 · Cited by 1,069
Marco, M. L., Sanders, M. E., Gänzle, M., Arrieta, M. C., Cotter, P. D., De Vuyst, L., Hill, C., Holzapfel, W., Lebeer, S., Merenstein, D., et al. (2021) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-020-00390-5 · Cited by 937
A Survey of Statistical Network Models
Goldenberg, A., Zheng, A. X., Fienberg, S. E., & Airoldi, E. M. (2010) · Foundations and Trends® in Machine Learning · doi:10.1561/2200000005 · Cited by 819
Yeast Genes That Enhance the Toxicity of a Mutant Huntingtin Fragment or α-Synuclein
Willingham, S., Outeiro, T. F., DeVit, M. J., Lindquist, S. L., & Muchowski, P. J. (2003) · Science · doi:10.1126/science.1090389 · Cited by 422
Metadata
- Authors
- Botstein, D., Chervitz, S. A., & Cherry, M.
- Venue
- Science
- Published
- 1997-08-29
- Volume
- 277
- Issue
- 5330
- Pages
- 1259-1260
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1606232948
- Cited by
- 474
- References
- 0
- FWCI
- 4.83
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.