The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Toroidal Structure of λ-Exonuclease
Abstract
Structure determination at 2.4 angstrom resolution shows that λ-exonuclease consists of three subunits that form a toroid. The central channel is funnel shaped, tapering from an inner diameter of about 30 angstroms at the wider end to 15 angstroms at the narrow end. This is adequate to accommodate the DNA substrate and thus provides a structural basis for the ability of the enzyme to sequentially hydrolyze thousands of nucleotides in a highly processive manner. The results also suggest the locations of the active sites and the constraints that limit cleavage to a single strand.
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Cites
PROCHECK: a program to check the stereochemical quality of protein structures
Laskowski, R. A., MacArthur, M. W., Moss, D. S., & Thornton, J. M. (1993) · Journal of Applied Crystallography · doi:10.1107/s0021889892009944 · Cited by 24,581
Protein Structure Comparison by Alignment of Distance Matrices
Holm, L., & Sander, C. (1993) · Journal of Molecular Biology · doi:10.1006/jmbi.1993.1489 · Cited by 3,984
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Yang, W. (2011) · Quarterly Reviews of Biophysics · doi:10.1017/s0033583510000181 · Cited by 692
En Passant Mutagenesis: A Two Step Markerless Red Recombination System
Tischer, B. K., Smith, G. A., & Osterrieder, N. (2010) · Methods in Molecular Biology · doi:10.1007/978-1-60761-652-8_30 · Cited by 599
Type II restriction endonucleases: structure and mechanism
Pingoud, A., Fuxreiter, M., Pingoud, V., & Wende, W. (2005) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-004-4513-1 · Cited by 489
Fu, J., Bian, X., Hu, S., Wang, H., Huang, F., Seibert, P. M., Plaza, A., Xia, L., Müller, R., Stewart, A. F., et al. (2012) · Nature Biotechnology · doi:10.1038/nbt.2183 · Cited by 448
Simultaneous detection and quantification of three bacterial meningitis pathogens by SERS
Gracie, K., Correa, E., Mabbott, S., Dougan, J. A., Graham, D., Goodacre, R., & Faulds, K. (2014) · Chem. Sci. · doi:10.1039/c3sc52875h · Cited by 161
Metadata
- Authors
- Kovall, R., & Matthews, B. W.
- Venue
- Science
- Published
- 1997-09-19
- Volume
- 277
- Issue
- 5333
- Pages
- 1824-1827
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2087997045
- Cited by
- 239
- References
- 2
- FWCI
- 11.44
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
