The DOI matches its Crossref record.
A Porous Silicon-Based Optical Interferometric Biosensor
Abstract
A biosensor has been developed based on induced wavelength shifts in the Fabry-Perot fringes in the visible-light reflection spectrum of appropriately derivatized thin films of porous silicon semiconductors. Binding of molecules induced changes in the refractive index of the porous silicon. The validity and sensitivity of the system are demonstrated for small organic molecules (biotin and digoxigenin), 16-nucleotide DNA oligomers, and proteins (streptavidin and antibodies) at pico- and femtomolar analyte concentrations. The sensor is also highly effective for detecting single and multilayered molecular assemblies.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Inverse design and demonstration of a compact and broadband on-chip wavelength demultiplexer
Piggott, A. Y., Lu, J., Lagoudakis, K. G., Petykiewicz, J., Babinec, T. M., & Vučković, J. (2015) · Nature Photonics · doi:10.1038/nphoton.2015.69 · Cited by 1,113
Lu, G., & Hupp, J. T. (2010) · Journal of the American Chemical Society · doi:10.1021/ja101415b · Cited by 1,082
Optical Amplification of Ligand-Receptor Binding Using Liquid Crystals
Gupta, V. K., Skaife, J. J., Dubrovsky, T. B., & Abbott, N. L. (1998) · Science · doi:10.1126/science.279.5359.2077 · Cited by 476
Metadata
- Authors
- Lin, V. S.-Y., Motesharei, K., Dancil, K.-P. S., Sailor, M. J., & Ghadiri, M. R.
- Venue
- Science
- Published
- 1997-10-31
- Volume
- 278
- Issue
- 5339
- Pages
- 840-843
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2006346404
- Cited by
- 1,299
- References
- 0
- FWCI
- 17.65
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: A Porous Silicon-Based Optical Interferometric Biosensor. https://app.cochat.ai/papers/10.1126/science.278.5339.840
- The paper
- Lin, V. S.-Y., Motesharei, K., Dancil, K.-P. S., Sailor, M. J., & Ghadiri, M. R. (1997). A Porous Silicon-Based Optical Interferometric Biosensor. Science. https://doi.org/10.1126/science.278.5339.840
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
