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Cited by 476

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Catalytic Galactose Oxidase Models: Biomimetic Cu(II)-Phenoxyl-Radical Reactivity

Wang, Yadong, DuBois, Jennifer L., Hedman, Britt, Hodgson, Keith O., Stack, T. D. P.·1998·Science

Abstract

Biomimetic functional models of the mononuclear copper enzyme galactose oxidase are presented that catalytically oxidize benzylic and allylic alcohols to aldehydes with O 2 under mild conditions. The mechanistic fidelity between the models and the natural system is pronounced. Modest structural mimicry proves sufficient to transfer an unusual ligand-based radical mechanism, previously unprecedented outside the protein matrix, to a simple chemical system.

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Metadata

Authors
Wang, Y., DuBois, J. L., Hedman, B., Hodgson, K. O., & Stack, T. D. P.
Venue
Science
Published
1998-01-23
Volume
279
Issue
5350
Pages
537-540
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W1992749453
Cited by
476
References
0
FWCI
16.93
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Catalytic Galactose Oxidase Models: Biomimetic Cu(II)-Phenoxyl-Radical Reactivity. https://app.cochat.ai/papers/10.1126/science.279.5350.537
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Wang, Y., DuBois, J. L., Hedman, B., Hodgson, K. O., & Stack, T. D. P. (1998). Catalytic Galactose Oxidase Models: Biomimetic Cu(II)-Phenoxyl-Radical Reactivity. Science. https://doi.org/10.1126/science.279.5350.537

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.