Student or educator? Sign up with your school email and get 6 months of Pro free.
Cited by 1,965

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

The Transcriptional Program in the Response of Human Fibroblasts to Serum

Iyer, Vishwanath R., Eisen, Michael B., Ross, Douglas T., Schuler, Greg, Moore, Troy, Lee, Jeffrey C. F., Trent, Jeffrey M., Staudt, Louis M., Hudson, James, Boguski, Mark S., Lashkari, Deval, Shalon, Dari, Botstein, David, Brown, Patrick O.·1999·Science

Abstract

The temporal program of gene expression during a model physiological response of human cells, the response of fibroblasts to serum, was explored with a complementary DNA microarray representing about 8600 different human genes. Genes could be clustered into groups on the basis of their temporal patterns of expression in this program. Many features of the transcriptional program appeared to be related to the physiology of wound repair, suggesting that fibroblasts play a larger and richer role in this complex multicellular response than had previously been appreciated.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1126/science.283.5398.83

Cites

1 of 1 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 1 references

Cited by

See all 1,965

Metadata

Authors
Iyer, V. R., Eisen, M. B., Ross, D. T., Schuler, G., Moore, T., Lee, J. C. F., Trent, J. M., Staudt, L. M., Hudson, J., Boguski, M. S., Lashkari, D., Shalon, D., Botstein, D., & Brown, P. O.
Venue
Science
Published
1999-01
Volume
283
Issue
5398
Pages
83-87
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2109970232
Cited by
1,965
References
1
FWCI
231.76
Type
journal article
Language
en
Open access
closed

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: The Transcriptional Program in the Response of Human Fibroblasts to Serum. https://app.cochat.ai/papers/10.1126/science.283.5398.83
The paper
Iyer, V. R., Eisen, M. B., Ross, D. T., Schuler, G., Moore, T., Lee, J. C. F., Trent, J. M., Staudt, L. M., Hudson, J., Boguski, M. S., Lashkari, D., Shalon, D., Botstein, D., & Brown, P. O. (1999). The Transcriptional Program in the Response of Human Fibroblasts to Serum. Science. https://doi.org/10.1126/science.283.5398.83

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.