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Cited by 317

The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.

UDP-GlcNAc 2-Epimerase: A Regulator of Cell Surface Sialylation

Keppler, Oliver T., Hinderlich, Stephan, Langner, Josmar, Schwartz-Albiez, Reinhard, Reutter, Werner, Pawlita, Michael·1999·Science

Abstract

Modification of cell surface molecules with sialic acid is crucial for their function in many biological processes, including cell adhesion and signal transduction. Uridine diphosphate- N -acetylglucosamine 2-epimerase (UDP-GlcNAc 2-epimerase) is an enzyme that catalyzes an early, rate-limiting step in the sialic acid biosynthetic pathway. UDP-GlcNAc 2-epimerase was found to be a major determinant of cell surface sialylation in human hematopoietic cell lines and a critical regulator of the function of specific cell surface adhesion molecules.

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Crossref · 10.1126/science.284.5418.1372

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Metadata

Authors
Keppler, O. T., Hinderlich, S., Langner, J., Schwartz-Albiez, R., Reutter, W., & Pawlita, M.
Venue
Science
Published
1999-05-21
Volume
284
Issue
5418
Pages
1372-1376
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2006527626
Cited by
317
References
41
FWCI
4.46
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: UDP-GlcNAc 2-Epimerase: A Regulator of Cell Surface Sialylation. https://app.cochat.ai/papers/10.1126/science.284.5418.1372
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Keppler, O. T., Hinderlich, S., Langner, J., Schwartz-Albiez, R., Reutter, W., & Pawlita, M. (1999). UDP-GlcNAc 2-Epimerase: A Regulator of Cell Surface Sialylation. Science. https://doi.org/10.1126/science.284.5418.1372

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.