The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
The Organization of Replication and Transcription
Abstract
Models for replication and transcription often display polymerases that track like locomotives along their DNA templates. However, recent evidence supports an alternative model in which DNA and RNA polymerases are immobilized by attachment to larger structures, where they reel in their templates and extrude newly made nucleic acids. These polymerases do not act independently; they are concentrated in discrete “factories,” where they work together on many different templates. Evidence for models involving tracking and immobile polymerases is reviewed.
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Cites
Visualization of Single RNA Transcripts in Situ
Femino, A. M., Fay, F. S., Fogarty, K., & Singer, R. H. (1998) · Science · doi:10.1126/science.280.5363.585 · Cited by 1,504
Cited by
Li, G., Ruan, X., Auerbach, R. K., Sandhu, K. S., Zheng, M., Wang, P., Poh, H. M., Goh, Y., Lim, J., Zhang, J., et al. (2012) · Cell · doi:10.1016/j.cell.2011.12.014 · Cited by 1,232
A framework for understanding the functions of biomolecular condensates across scales
Lyon, A. S., Peeples, W. B., & Rosen, M. K. (2021) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-020-00303-z · Cited by 895
Maintaining genome stability at the replication fork
Branzei, D., & Foiani, M. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2852 · Cited by 786
Protein Dynamics: Implications for Nuclear Architecture and Gene Expression
Misteli, T. (2001) · Science · doi:10.1126/science.291.5505.843 · Cited by 668
RNA polymerase II clustering through carboxy-terminal domain phase separation
Boehning, M., Dugast-Darzacq, C., Rankovic, M., Hansen, A. S., Yu, T., Marie-Nelly, H., McSwiggen, D. T., Kokic, G., Dailey, G. M., Cramer, P., et al. (2018) · Nature Structural & Molecular Biology · doi:10.1038/s41594-018-0112-y · Cited by 601
Metadata
- Authors
- Cook, P. R.
- Venue
- Science
- Published
- 1999-06-11
- Volume
- 284
- Issue
- 5421
- Pages
- 1790-1795
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2035659472
- Cited by
- 750
- References
- 1
- FWCI
- 16.75
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
