The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Setting the Standards: Quality Control in the Secretory Pathway
Abstract
A variety of quality control mechanisms operate in the endoplasmic reticulum and in downstream compartments of the secretory pathway to ensure the fidelity and regulation of protein expression during cell life and differentiation. As a rule, only proteins that pass a stringent selection process are transported to their target organelles and compartments. If proper maturation fails, the aberrant products are degraded. Quality control improves folding efficiency by retaining proteins in the special folding environment of the endoplasmic reticulum, and it prevents harmful effects that could be caused by the deployment of incompletely folded or assembled proteins.
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Cites
Principles that Govern the Folding of Protein Chains
Anfinsen, C. B. (1973) · Science · doi:10.1126/science.181.4096.223 · Cited by 7,096
Hammond, C., Braakman, I., & Helenius, A. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.3.913 · Cited by 841
Self-citationHammond, C., & Helenius, A. (1994) · The Journal of cell biology · doi:10.1083/jcb.126.1.41 · Cited by 443
Self-citationJakob, C. A., Burda, P., Roth, J., & Aebi, M. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.142.5.1223 · Cited by 338
The Hdj‐2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis
Meacham, G. C., Lu, Z., King, S., Sorscher, E., Tousson, A., & Cyr, D. M. (1999) · The EMBO Journal · doi:10.1093/emboj/18.6.1492 · Cited by 335
Cited by
Roles of N-Linked Glycans in the Endoplasmic Reticulum
Helenius, A., & Aebi, M. (2004) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.73.011303.073752 · Cited by 2,037
Self-citationAggresomes, inclusion bodies and protein aggregation
Kopito, R. R. (2000) · Trends in Cell Biology · doi:10.1016/s0962-8924(00)01852-3 · Cited by 1,921
Autosomal dominant polycystic kidney disease
Torres, V. E., Harris, P. C., & Pirson, Y. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60601-1 · Cited by 1,550
Shen, J., Chen, X., Hendershot, L., & Prywes, R. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00203-4 · Cited by 1,456
Inoue, S., Tanaka, K., Arisaka, F., Kimura, S., Ohtomo, K., & Mizuno, S. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m006897200 · Cited by 784
Metadata
- Authors
- Ellgaard, L., Molinari, M., & Helenius, A.
- Venue
- Science
- Published
- 1999-12-03
- Volume
- 286
- Issue
- 5446
- Pages
- 1882-1888
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2045893780
- Cited by
- 1,192
- References
- 5
- FWCI
- 34.94
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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