The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Rad6-Dependent Ubiquitination of Histone H2B in Yeast
Abstract
Although ubiquitinated histones are present in substantial levels in vertebrate cells, the roles they play in specific biological processes and the cellular factors that regulate this modification are not well characterized. Ubiquitinated H2B (uH2B) has been identified in the yeast Saccharomyces cerevisiae , and mutation of the conserved ubiquitination site is shown to confer defects in mitotic cell growth and meiosis. uH2B was not detected in rad6 mutants, which are defective for the ubiquitin-conjugating enzyme Ubc2, thus identifying Rad6 as the major cellular activity that ubiquitinates H2B in yeast.
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Cites
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Cited by
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Metadata
- Authors
- Robzyk, K., Recht, J., & Osley, M. A.
- Venue
- Science
- Published
- 2000-01-21
- Volume
- 287
- Issue
- 5452
- Pages
- 501-504
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1977188840
- Cited by
- 666
- References
- 36
- FWCI
- 12.05
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
