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Cited by 1,538

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

A Whole-Genome Assembly of Drosophila

Myers, Eugene W., Sutton, Granger G., Delcher, Art L., Dew, Ian M., Fasulo, Dan P., Flanigan, Michael J., Kravitz, Saul A., Mobarry, Clark M., Reinert, Knut H. J., Remington, Karin A., Anson, Eric L., Bolanos, Randall A., Chou, Hui-Hsien, Jordan, Catherine M., Halpern, Aaron L., Lonardi, Stefano, Beasley, Ellen M., Brandon, Rhonda C., Chen, Lin, Dunn, Patrick J., Lai, Zhongwu, Liang, Yong, Nusskern, Deborah R., Zhan, Ming, Zhang, Qing, Zheng, Xiangqun, Rubin, Gerald M., Adams, Mark D., Venter, J. Craig·2000·Science

Abstract

We report on the quality of a whole-genome assembly of Drosophila melanogaster and the nature of the computer algorithms that accomplished it. Three independent external data sources essentially agree with and support the assembly's sequence and ordering of contigs across the euchromatic portion of the genome. In addition, there are isolated contigs that we believe represent nonrepetitive pockets within the heterochromatin of the centromeres. Comparison with a previously sequenced 2.9- megabase region indicates that sequencing accuracy within nonrepetitive segments is greater than 99.99% without manual curation. As such, this initial reconstruction of the Drosophila sequence should be of substantial value to the scientific community.

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Crossref · 10.1126/science.287.5461.2196

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Metadata

Authors
Myers, E. W., Sutton, G. G., Delcher, A. L., Dew, I. M., Fasulo, D. P., Flanigan, M. J., Kravitz, S. A., Mobarry, C. M., Reinert, K. H. J., Remington, K. A., Anson, E. L., Bolanos, R. A., Chou, H.-H., Jordan, C. M., Halpern, A. L., Lonardi, S., Beasley, E. M., Brandon, R. C., Chen, L., Dunn, P. J., Lai, Z., Liang, Y., Nusskern, D. R., Zhan, M., Zhang, Q., Zheng, X., Rubin, G. M., Adams, M. D., & Venter, J. C.
Venue
Science
Published
2000-03-24
Volume
287
Issue
5461
Pages
2196-2204
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W1635391495
Cited by
1,538
References
3
FWCI
21.97
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: A Whole-Genome Assembly of Drosophila. https://app.cochat.ai/papers/10.1126/science.287.5461.2196
The paper
Myers, E. W., Sutton, G. G., Delcher, A. L., Dew, I. M., Fasulo, D. P., Flanigan, M. J., Kravitz, S. A., Mobarry, C. M., Reinert, K. H. J., Remington, K. A., Anson, E. L., Bolanos, R. A., Chou, H.-H., Jordan, C. M., Halpern, A. L., Lonardi, S., Beasley, E. M., Brandon, R. C., Chen, L., . . . Venter, J. C. (2000). A Whole-Genome Assembly of Drosophila. Science. https://doi.org/10.1126/science.287.5461.2196

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.