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A Pseudoautosomal Gene in Man
Abstract
The X/Y homologous gene MIC2 was shown to exchange between the sex chromosomes, thus demonstrating that it is a pseudoautosomal gene in man. MIC2 recombines with the sex-determining gene(s) TDF at a frequency of 2 to 3 percent. It is the most proximal pseudoautosomal locus thus far described and as such is an important marker for use in studies directed towards the isolation of TDF .
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Citations
Cited by
The Human Y Chromosome: Overlapping DNA Clones Spanning the Euchromatic Region
Foote, S., Vollrath, D., Hilton, A., & Page, D. C. (1992) · Science · doi:10.1126/science.1359640 · Cited by 386
Human and mouse amelogenin gene loci are on the sex chromosomes
Lau, E. C., Mohandas, T. K., Shapiro, L. J., Slavkin, H. C., & Snead, M. L. (1989) · Genomics · doi:10.1016/0888-7543(89)90295-4 · Cited by 306
Yen, P. H., Allen, E., Marsh, B., Mohandas, T., Wang, N., Taggart, R. T., & Shapiro, L. J. (1987) · Cell · doi:10.1016/0092-8674(87)90447-8 · Cited by 269
The Continuum of Psychosis and Its Genetic Origins: The Sixty-fifth Maudsley Lecture
Crow, T. J. (1990) · British Journal of Psychiatry · doi:10.1192/bjp.156.6.788 · Cited by 264
Metadata
- Authors
- Goodfellow, P. J., Darling, S. M., Thomas, N. S., & Goodfellow, P. N.
- Venue
- Science
- Published
- 1986-11-07
- Volume
- 234
- Issue
- 4777
- Pages
- 740-743
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2025680394
- Cited by
- 201
- References
- 0
- FWCI
- 13.73
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: A Pseudoautosomal Gene in Man. https://app.cochat.ai/papers/10.1126/science.2877492
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- Goodfellow, P. J., Darling, S. M., Thomas, N. S., & Goodfellow, P. N. (1986). A Pseudoautosomal Gene in Man. Science. https://doi.org/10.1126/science.2877492
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
