The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Control of Homeostasis of CD8 + Memory T Cells by Opposing Cytokines
Abstract
Memory T cells maintain their numbers for long periods after antigen exposure. Here we show that CD8 + T cells of memory phenotype divide slowly in animals. This division requires interleukin-15 and is markedly increased by inhibition of interleukin-2 (IL-2). Therefore, the numbers of CD8 + memory T cells in animals are controlled by a balance between IL-15 and IL-2.
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Citations
Cites
Turnover of naive- and memory-phenotype T cells.
Tough, D. F., & Sprent, J. (1994) · The Journal of experimental medicine · doi:10.1084/jem.179.4.1127 · Cited by 869
Cited by
Effector and memory T-cell differentiation: implications for vaccine development
Kaech, S. M., Wherry, E. J., & Ahmed, R. (2002) · Nature Reviews Immunology · doi:10.1038/nri778 · Cited by 1,865
Lineage relationship and protective immunity of memory CD8 T cell subsets
Wherry, E. J., Teichgräber, V., Becker, T. C., Masopust, D., Kaech, S. M., Antia, R., von Andrian, U. H., & Ahmed, R. (2003) · Nature Immunology · doi:10.1038/ni889 · Cited by 1,864
Kaech, S. M., Tan, J. T., Wherry, E. J., Konieczny, B. T., Surh, C. D., & Ahmed, R. (2003) · Nature Immunology · doi:10.1038/ni1009 · Cited by 1,830
Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development
van der Windt, G. J. W., Everts, B., Chang, C.-H., Curtis, J. D., Freitas, T. C., Amiel, E., Pearce, E. J., & Pearce, E. L. (2012) · Immunity · doi:10.1016/j.immuni.2011.12.007 · Cited by 1,540
Brenchley, J. M., Karandikar, N. J., Betts, M. R., Ambrozak, D. R., Hill, B. J., Crotty, L. E., Casazza, J. P., Kuruppu, J., Migueles, S. A., Connors, M., et al. (2003) · Blood · doi:10.1182/blood-2002-07-2103 · Cited by 1,073
Metadata
- Authors
- Ku, C. C., Murakami, M., Sakamoto, A., Kappler, J., & Marrack, P.
- Venue
- Science
- Published
- 2000-04-28
- Volume
- 288
- Issue
- 5466
- Pages
- 675-678
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1997196319
- Cited by
- 816
- References
- 1
- FWCI
- 33.19
- Type
- journal article
- Language
- en
- Open access
- closed
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- Ku, C. C., Murakami, M., Sakamoto, A., Kappler, J., & Marrack, P. (2000). Control of Homeostasis of CD8 + Memory T Cells by Opposing Cytokines. Science. https://doi.org/10.1126/science.288.5466.675
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
