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Direct Targeting of Light Signals to a Promoter Element-Bound Transcription Factor
Abstract
Light signals perceived by the phytochrome family of sensory photoreceptors are transduced to photoresponsive genes by an unknown mechanism. Here, we show that the basic helix-loop-helix transcription factor PIF3 binds specifically to a G-box DNA-sequence motif present in various light-regulated gene promoters, and that phytochrome B binds reversibly to G-box–bound PIF3 specifically upon light-triggered conversion of the photoreceptor to its biologically active conformer. We suggest that the phytochromes may function as integral light-switchable components of transcriptional regulator complexes, permitting continuous and immediate sensing of changes in this environmental signal directly at target gene promoters.
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Citations
Cited by
Phytochromes and light signal perception by plants—an emerging synthesis
Smith, H. (2000) · Nature · doi:10.1038/35036500 · Cited by 1,380
Light-Regulated Plant Growth and Development
Kami, C., Lorrain, S., Hornitschek, P., & Fankhauser, C. (2010) · Current Topics in Developmental Biology · doi:10.1016/s0070-2153(10)91002-8 · Cited by 927
Genetics of Aux/IAA and ARF action in plant growth and development
Liscum, E., & Reed, J. W. (2002) · Auxin Molecular Biology · doi:10.1007/978-94-010-0377-3_10 · Cited by 597
Phytochrome Signaling Mechanisms
Li, J., Li, G., Wang, H., & Wang Deng, X. (2011) · The Arabidopsis Book · doi:10.1199/tab.0148 · Cited by 561
Decoding of Light Signals by Plant Phytochromes and Their Interacting Proteins
Bae, G., & Choi, G. (2008) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.59.032607.092859 · Cited by 490
Metadata
- Authors
- Martı́nez-Garcı́a, J. F., Huq, E., & Quail, P. H.
- Venue
- Science
- Published
- 2000-05-05
- Volume
- 288
- Issue
- 5467
- Pages
- 859-863
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2069812226
- Cited by
- 687
- References
- 0
- FWCI
- 90.98
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
