The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
Molecular Analysis of FRIGIDA , a Major Determinant of Natural Variation in Arabidopsis Flowering Time
Abstract
Vernalization, the acceleration of flowering by a long period of cold temperature, ensures that many plants overwinter vegetatively and flower in spring. In Arabidopsis , allelic variation at the FRIGIDA ( FRI ) locus is a major determinant of natural variation in flowering time. Dominant alleles of FRI confer late flowering, which is reversed to earliness by vernalization. We cloned FRI and analyzed the molecular basis of the allelic variation. Most of the early-flowering ecotypes analyzed carry FRI alleles containing one of two different deletions that disrupt the open reading frame. Loss-of-function mutations at FRI have thus provided the basis for the evolution of many early-flowering ecotypes.
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Cites
FLOWERING LOCUS C Encodes a Novel MADS Domain Protein That Acts as a Repressor of Flowering
Michaels, S. D., & Amasino, R. M. (1999) · The Plant Cell · doi:10.1105/tpc.11.5.949 · Cited by 1,992
Self-citationSheldon, C. C., Burn, J. E., Perez, P. P., Metzger, J., Edwards, J. A., Peacock, W. J., & Dennis, E. S. (1999) · The Plant Cell · doi:10.1105/tpc.11.3.445 · Cited by 971
Simpson, G. G., Gendall, A. R., & Dean, C. (1999) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.15.1.519 · Cited by 269
Self-citationLee, I., Michaels, S. D., Masshardt, A. S., & Amasino, R. M. (1994) · The Plant Journal · doi:10.1046/j.1365-313x.1994.6060903.x · Cited by 254
Self-citationAlonso‐Blanco, C., El‐Assal, S. E., Coupland, G., & Koornneef, M. (1998) · Genetics · doi:10.1093/genetics/149.2.749 · Cited by 245
Koornneef, M., Blankestijn‐de Vries, H., Hanhart, C., Soppe, W., & Peeters, T. (1994) · The Plant Journal · doi:10.1046/j.1365-313x.1994.6060911.x · Cited by 236
Mapping FRI, a locus controlling flowering time and vernalization response in Arabidopsis thaliana
Clarke, J. H., & Dean, C. (1994) · Molecular and General Genetics MGG · doi:10.1007/bf00277351 · Cited by 194
Self-citationGenetic Variation Within and Among Populations of Arabidopsis thaliana
Bergelson, J. M., Stahl, E. A., DUDEK, S. M., & Kreitman, M. (1998) · Genetics · doi:10.1093/genetics/148.3.1311 · Cited by 187
Analysis of naturally occurring late flowering in Arabidopsis thaliana
Lee, I., Bleecker, A., & Amasino, R. (1993) · Molecular and General Genetics MGG · doi:10.1007/bf00282798 · Cited by 164
Self-citationMitchell‐Olds, T. (1996) · Evolution · doi:10.1111/j.1558-5646.1996.tb04480.x · Cited by 155
Cited by
Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines
Atwell, S., Huang, Y. S., Vilhjálmsson, B. J., Willems, G., Horton, M., Li, Y., Meng, D., Platt, A., Tarone, A. M., Hu, T. T., et al. (2010) · Nature · doi:10.1038/nature08800 · Cited by 1,780
Self-citationThe genetic basis of flowering responses to seasonal cues
Andrés, F., & Coupland, G. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3291 · Cited by 1,538
Seasonal and developmental timing of flowering
Amasino, R. (2010) · The Plant Journal · doi:10.1111/j.1365-313x.2010.04148.x · Cited by 894
Self-citationThe genetic causes of convergent evolution
Stern, D. L. (2013) · Nature Reviews Genetics · doi:10.1038/nrg3483 · Cited by 818
Stinchcombe, J. R., & Hoekstra, H. E. (2008) · Heredity · doi:10.1038/sj.hdy.6800937 · Cited by 622
Metadata
- Authors
- Johanson, U., West, J., Lister, C., Michaels, S., Amasino, R., & Dean, C.
- Venue
- Science
- Published
- 2000-10-13
- Volume
- 290
- Issue
- 5490
- Pages
- 344-347
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2066672169
- Cited by
- 1,019
- References
- 15
- FWCI
- 49.03
- Type
- journal article
- Language
- en
- Open access
- closed
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- Johanson, U., West, J., Lister, C., Michaels, S., Amasino, R., & Dean, C. (2000). Molecular Analysis of FRIGIDA , a Major Determinant of Natural Variation in Arabidopsis Flowering Time. Science. https://doi.org/10.1126/science.290.5490.344
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
