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Aureusidin Synthase: A Polyphenol Oxidase Homolog Responsible for Flower Coloration
Abstract
Aurones are plant flavonoids that provide yellow color to the flowers of some popular ornamental plants, such as snapdragon and cosmos. In this study, we have identified an enzyme responsible for the synthesis of aurone from chalcones in the yellow snapdragon flower. The enzyme (aureusidin synthase) is a 39-kilodalton, copper-containing glycoprotein catalyzing the hydroxylation and/or oxidative cyclization of the precursor chalcones, 2′,4′,6′,4-tetrahydroxychalcone and 2′,4′,6′,3,4-pentahydroxychalcone. The complementary DNA encoding aureusidin synthase is expressed in the petals of aurone-containing varieties. DNA sequence analysis revealed that aureusidin synthase belongs to the plant polyphenol oxidase family, providing an unequivocal example of the function of the polyphenol oxidase homolog in plants, i.e., flower coloration.
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Citations
Cited by
Biosynthesis of plant pigments: anthocyanins, betalains and carotenoids
Tanaka, Y., Sasaki, N., & Ohmiya, A. (2008) · The Plant Journal · doi:10.1111/j.1365-313x.2008.03447.x · Cited by 2,434
Self-citationCopper Active Sites in Biology
Solomon, E. I., Heppner, D. E., Johnston, E. M., Ginsbach, J. W., Cirera, J., Qayyum, M., Kieber-Emmons, M. T., Kjaergaard, C. H., Hadt, R. G., & Tian, L. (2014) · Chemical Reviews · doi:10.1021/cr400327t · Cited by 1,751
The Flavonoid Biosynthesis Network in Plants
Liu, W., Feng, Y., Yu, S., Fan, Z., Li, X., Li, J., & Yin, H. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222312824 · Cited by 1,020
Recent advances in betalain research
Strack, D., Vogt, T., & Schliemann, W. (2003) · Phytochemistry · doi:10.1016/s0031-9422(02)00564-2 · Cited by 802
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Metadata
- Authors
- Nakayama, T., Yonekura-Sakakibara, K., Sato, T., Kikuchi, S., Fukui, Y., Fukuchi-Mizutani, M., Ueda, T., Nakao, M., Tanaka, Y., Kusumi, T., & Nishino, T.
- Venue
- Science
- Published
- 2000-11-10
- Volume
- 290
- Issue
- 5494
- Pages
- 1163-1166
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2104888949
- Cited by
- 250
- References
- 0
- FWCI
- 2.25
- Type
- journal article
- Language
- en
- Open access
- closed
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- The paper
- Nakayama, T., Yonekura-Sakakibara, K., Sato, T., Kikuchi, S., Fukui, Y., Fukuchi-Mizutani, M., Ueda, T., Nakao, M., Tanaka, Y., Kusumi, T., & Nishino, T. (2000). Aureusidin Synthase: A Polyphenol Oxidase Homolog Responsible for Flower Coloration. Science. https://doi.org/10.1126/science.290.5494.1163
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