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Cited by 257

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Guidance of Cell Migration by EGF Receptor Signaling During Drosophila Oogenesis

Duchek, Peter, Rørth, Pernille·2001·Science

Abstract

Directed cell migration is important for many aspects of normal animal development, but little is known about how cell migrations are guided or the mechanisms by which guidance cues are translated into directed cell movement. Here we present evidence that signaling mediated by the epidermal growth factor receptor (EGFR) guides dorsal migration of border cells during Drosophila oogenesis. The transforming growth factor–α (TGF-α)–like ligand Gurken appears to serve as the guidance cue. To mediate this guidance function, EGFR signals via a pathway that is independent of Raf-MAP kinase and receptor-specific.

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Metadata

Authors
Duchek, P., & Rørth, P.
Venue
Science
Published
2001-01-05
Volume
291
Issue
5501
Pages
131-133
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2095065858
Cited by
257
References
1
FWCI
6.38
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Guidance of Cell Migration by EGF Receptor Signaling During Drosophila Oogenesis. https://app.cochat.ai/papers/10.1126/science.291.5501.131
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Duchek, P., & Rørth, P. (2001). Guidance of Cell Migration by EGF Receptor Signaling During Drosophila Oogenesis. Science. https://doi.org/10.1126/science.291.5501.131

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.