The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
YIGSR, a Synthetic Laminin Pentapeptide, Inhibits Experimental Metastasis Formation
Abstract
The invasion of tumor cells through basement membranes is a critical step in the formation of metastases. The binding of the malignant cells to laminin in the basement membranes allows their attachment and activates their invasiveness. Recently a synthetic nonapeptide from the B1 chain sequence of laminin was identified as a major site for cell binding. A pentapeptide within the nonapeptide sequence was found to reduce the formation of lung colonies in mice injected with melanoma cells and also to inhibit the invasiveness of the cells in vitro.
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Cites
Laminin–a glycoprotein from basement membranes
Timpl, R., Rohde, H., Robey, P. G., Rennard, S. I., Foidart, J. M., & Martin, G. R. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)83607-4 · Cited by 2,378
Self-citationA rapid in vitro assay for quantitating the invasive potential of tumor cells.
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Self-citationBasement membrane complexes with biological activity
Kleinman, H. K., McGarvey, M. L., Hassell, J. R., Star, V. L., Cannon, F. B., Laurie, G. W., & Martin, G. R. (1986) · Biochemistry · doi:10.1021/bi00350a005 · Cited by 1,502
Self-citationArg-Gly-Asp: A versatile cell recognition signal
Ruoslahti, E., & Pierschbacher, M. D. (1986) · Cell · doi:10.1016/0092-8674(86)90259-x · Cited by 1,397
Selection of Successive Tumour Lines for Metastasis
FIDLER, I. J. (1973) · Nature New Biology · doi:10.1038/newbio242148a0 · Cited by 1,361
Graf, J., Iwamoto, Y., Sasaki, M., Martin, G. R., Kleinman, H. K., Robey, F. A., & Yamada, Y. (1987) · Cell · doi:10.1016/0092-8674(87)90707-0 · Cited by 671
Self-citationEngel, J., Odermatt, E., Engel, A., Madri, J. A., Furthmayr, H., Rohde, H., & Timpl, R. (1981) · Journal of Molecular Biology · doi:10.1016/0022-2836(81)90326-0 · Cited by 667
A Synthetic Peptide from Fibronectin Inhibits Experimental Metastasis of Murine Melanoma Cells
Humphries, M. J., Olden, K., & Yamada, K. M. (1986) · Science · doi:10.1126/science.3726541 · Cited by 626
Biological activities of laminin
Kleinman, H. K., Cannon, F. B., Laurie, G. W., Hassell, J. R., Aumailley, M., Terranova, V. P., Martin, G. R., & DuBois‐Dalcq, M. (1985) · Journal of Cellular Biochemistry · doi:10.1002/jcb.240270402 · Cited by 463
Self-citationIsolation of a cell surface receptor protein for laminin from murine fibrosarcoma cells.
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Cited by
Biomimetic materials for tissue engineering
Shin, H., Jo, S., & Mikos, A. G. (2003) · Biomaterials · doi:10.1016/s0142-9612(03)00339-9 · Cited by 1,612
Tumor interactions with the vasculature: angiogenesis and tumor metastasis
Blood, C. (1990) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/0304-419x(90)90014-r · Cited by 593
Nicolson, G. L. (1988) · CANCER AND METASTASIS REVIEW · doi:10.1007/bf00046483 · Cited by 502
Nierodzik, M. L., & Karpatkin, S. (2006) · Cancer Cell · doi:10.1016/j.ccr.2006.10.002 · Cited by 502
Fox, G., Parry, N. R., Barnett, P. V., McGinn, B., Rowlands, D. J., & Brown, F. (1989) · Journal of General Virology · doi:10.1099/0022-1317-70-3-625 · Cited by 389
Metadata
- Authors
- Iwamoto, Y., Robey, F. A., Graf, J., Sasaki, M., Kleinman, H. K., Yamada, Y., & Martin, G. R.
- Venue
- Science
- Published
- 1987-11-20
- Volume
- 238
- Issue
- 4830
- Pages
- 1132-1134
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1969176764
- Cited by
- 552
- References
- 25
- FWCI
- 10.16
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: YIGSR, a Synthetic Laminin Pentapeptide, Inhibits Experimental Metastasis Formation. https://app.cochat.ai/papers/10.1126/science.2961059
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- Iwamoto, Y., Robey, F. A., Graf, J., Sasaki, M., Kleinman, H. K., Yamada, Y., & Martin, G. R. (1987). YIGSR, a Synthetic Laminin Pentapeptide, Inhibits Experimental Metastasis Formation. Science. https://doi.org/10.1126/science.2961059
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
