The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Infection of HTLV-III/LAV in HTLV-I-Carrying Cells MT-2 and MT-4 and Application in a Plaque Assay
Abstract
The human T-cell lines MT-2 and MT-4 carry the human T-cell leukemia virus type I (HTLV-I). When MT-2 and MT-4 were infected with HTLV-III, the probable etiologic agent of the acquired immune deficiency syndrome (AIDS), rapid cytopathogenic effects and cytotoxicity were observed that made it possible to titrate the biologically active virus in a plaque-forming assay. The cytopathogenic effects were preceded by the rapid induction and increase of HTLV-III antigens as revealed by immunofluorescence and immunoprecipitation. Activities of HTLV-III were neutralized by the human antibodies against the virus when immunofluorescence and plaque assays were used. Essentially the same results were obtained with the lymphadenopathy-associated virus (LAV 1 ).
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Poiesz, B. J., Ruscetti, F. W., Gazdar, A. F., Bunn, P. A., Minna, J. D., & Gallo, R. C. (1980) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.77.12.7415 · Cited by 5,043
Sodroski, J. G., Rosen, C. A., & Haseltine, W. A. (1984) · Science · doi:10.1126/science.6330891 · Cited by 770
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Metadata
- Authors
- Harada, S., Koyanagi, Y., & Yamamoto, N.
- Venue
- Science
- Published
- 1985-08-09
- Volume
- 229
- Issue
- 4713
- Pages
- 563-566
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2015326137
- Cited by
- 857
- References
- 2
- FWCI
- 9.32
- Type
- journal article
- Language
- en
- Open access
- closed
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- Harada, S., Koyanagi, Y., & Yamamoto, N. (1985). Infection of HTLV-III/LAV in HTLV-I-Carrying Cells MT-2 and MT-4 and Application in a Plaque Assay. Science. https://doi.org/10.1126/science.2992081
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