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Cited by 391

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The Biology and Chemistry of Fertilization

Wassarman, Paul M.·1987·Science

Abstract

Fertilization of eggs by sperm, the means by which sexual reproduction takes place in nearly all multicellular organisms, is fundamental to the maintenance of life. In both mammals and nonmammals, the pathway that leads to fusion of an egg with a single sperm consists of many steps that occur in a compulsory order. These steps include species-specific cellular recognition, intracellular and intercellular membrane fusions, and enzyme-catalyzed modifications of cellular investments. In several instances, the molecular mechanisms that underlie these events during mammalian fertilization are beginning to be revealed.

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Metadata

Authors
Wassarman, P. M.
Venue
Science
Published
1987-01-30
Volume
235
Issue
4788
Pages
553-560
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2094722022
Cited by
391
References
0
FWCI
45.74
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The Biology and Chemistry of Fertilization. https://app.cochat.ai/papers/10.1126/science.3027891
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Wassarman, P. M. (1987). The Biology and Chemistry of Fertilization. Science. https://doi.org/10.1126/science.3027891

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.