The DOI matches its Crossref record.
Induction of B Cell Unresponsiveness to Noninherited Maternal HLA Antigens During Fetal Life
Abstract
Patients who have received many transfusions become highly sensitized and develop antibodies against almost all HLA alloantigens, so that finding a cross-match negative kidney donor is difficult. A survey of those patients showed that 50 percent did not form antibodies against the noninherited maternal HLA antigens. Apart from the obvious clinical implications, the data indicate that a human equivalent of murine neonatal or actively acquired tolerance has now been identified.
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Cited by
Maternal Alloantigens Promote the Development of Tolerogenic Fetal Regulatory T Cells in Utero
Mold, J. E., Michaëlsson, J., Burt, T. D., Muench, M. O., Beckerman, K. P., Busch, M. P., Lee, T.-H., Nixon, D. F., & McCune, J. M. (2008) · Science · doi:10.1126/science.1164511 · Cited by 836
Fetal and Adult Hematopoietic Stem Cells Give Rise to Distinct T Cell Lineages in Humans
Mold, J. E., Venkatasubrahmanyam, S., Burt, T. D., Michaëlsson, J., Rivera, J. M., Galkina, S. A., Weinberg, K., Stoddart, C. A., & McCune, J. M. (2010) · Science · doi:10.1126/science.1196509 · Cited by 444
Metadata
- Authors
- Claas, F. H. J., Gijbels, Y., van der Velden-de Munck, J., & van Rood, J. J.
- Venue
- Science
- Published
- 1988-09-30
- Volume
- 241
- Issue
- 4874
- Pages
- 1815-1817
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1976289976
- Cited by
- 265
- References
- 0
- FWCI
- 4.07
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Induction of B Cell Unresponsiveness to Noninherited Maternal HLA Antigens During Fetal Life. https://app.cochat.ai/papers/10.1126/science.3051377
- The paper
- Claas, F. H. J., Gijbels, Y., van der Velden-de Munck, J., & van Rood, J. J. (1988). Induction of B Cell Unresponsiveness to Noninherited Maternal HLA Antigens During Fetal Life. Science. https://doi.org/10.1126/science.3051377
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
