Spiraling Costs Threaten Gridlock
Open accessAbstract
The gold standard of medical science--the big randomized trial--is in danger of being priced out of reach by technical complexity, poor management, and paperwork.
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Recruitment of trial participants is easier in developing countries than in the developed world.
“Recruitment of trial participants is easier than in the developed world; large outcome trials that require enrolment of thousands of patients could make huge savings for the sponsor if the trial is conducted outside of developed countries [74].”
From Barriers for conducting clinical trials in developing countries—A systematic review (2018) · cites this paper as [74]
Large outcome trials requiring enrolment of thousands of patients could make huge savings for the sponsor if conducted outside developed countries.
“Recruitment of trial participants is easier than in the developed world; large outcome trials that require enrolment of thousands of patients could make huge savings for the sponsor if the trial is conducted outside of developed countries [74].”
From Barriers for conducting clinical trials in developing countries—A systematic review (2018) · cites this paper as [74]
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“[18] Malakoff D.”
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- Authors
- Malakoff, D.
- Affiliations
- David Malakoff is a writer in Alexandria, Virginia.
- Corresponding author
- Malakoff, David
- Venue
- Science
- Published
- 2008-10-10
- Volume
- 322
- Issue
- 5899
- Pages
- 210-213
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2079246736
- Cited by
- 33
- References
- 0
- Citations by year
- 2023: 2 · 2022: 1 · 2021: 2 · 2019: 2 · 2018: 2 · 2017: 3 · 2016: 1 · 2015: 2 · 2013: 4 · 2012: 1
- FWCI
- 4.29
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health and Medical Research Impacts
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ethics in Clinical Research
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
- Keywords
- randomized controlled trials, trial costs, clinical trial management, research costs
- MeSH terms
- Clinical Protocols, Costs and Cost Analysis, Humans, United States, Randomized Controlled Trials as Topic, Drug Approval, Clinical Trials, Phase I as Topic, Clinical Trials, Phase II as Topic, Clinical Trials, Phase III as Topic, Patient Selection
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