The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
A Bactericidal Effect for Human Lactoferrin
Abstract
Streptococcus mutans and Vibrio cholerae , but not Escherichia coli , were killed by incubation with purified human apolactoferrin. Concentrations of lactoferrin below that necessary for total inhibition resulted in a marked reduction in viable colony-forming units. This bactericidal effect was contingent upon the metal-chelating properties of the lactoferrin molecule.
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Citations
Cites
Iron-binding Proteins in Milk and Resistance to Escherichia coli Infection in Infants
Bullen, J. J., Rogers, H. J., & Leigh, L. (1972) · BMJ · doi:10.1136/bmj.1.5792.69 · Cited by 655
Weinberg, E. D. (1974) · Science · doi:10.1126/science.184.4140.952 · Cited by 579
An iron-binding protein common to many external secretions
Masson, P. L., Heremans, J. F., & Dive, C. H. (1966) · Clinica Chimica Acta · doi:10.1016/0009-8981(66)90004-0 · Cited by 577
Iron-Binding Catechols and Virulence in Escherichia coli
Rogers, H. J. (1973) · Infection and Immunity · doi:10.1128/iai.7.3.445-456.1973 · Cited by 381
Mycobactins: iron-chelating growth factors from mycobacteria
Snow, G. A. (1970) · Bacteriological Reviews · doi:10.1128/br.34.2.99-125.1970 · Cited by 378
Character of azurophil and specific granules purified from human polymorphonuclear leukocytes.
Spitznagel, J. K., Fg, D., Leffell, M. S., et al. (1974) · PubMed · Cited by 337
Inhibition of bacteria by lactoferrin and other iron-chelating agents
Oram, J. D., & Reiter, B. (1968) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(68)90015-9 · Cited by 313
ASSOCIATION OF LACTOFERRIN WITH SPECIFIC GRANULES IN RABBIT HETEROPHIL LEUKOCYTES
Baggiolini, M., de Duve, C., Masson, P. L., & Heremans, J. F. (1970) · The Journal of Experimental Medicine · doi:10.1084/jem.131.3.559 · Cited by 269
Clinical Aspects of Cardiomyopathy
Goodwin, J. F., Gordon, H., Hollman, A., & Bishop, M. B. (1961) · BMJ · doi:10.1136/bmj.1.5219.69 · Cited by 260
Kochan, I. (1973) · Current Topics in Microbiology and Immunology · doi:10.1007/978-3-642-65502-9_1 · Cited by 237
Cited by
Identification of the bactericidal domain of lactoferrin
Bellamy, W., Takase, M., Yamauchi, K., Wakabayashi, H., Kawase, K., & Tomita, M. (1992) · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · doi:10.1016/0167-4838(92)90346-f · Cited by 892
Killing of gram-negative bacteria by lactoferrin and lysozyme.
Ellison, R. T., & Giehl, T. J. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115407 · Cited by 746
The significance of iron in infection
Bullen, J. J. (1981) · Clinical Infectious Diseases · doi:10.1093/clinids/3.6.1127 · Cited by 603
Biomedical applications of nisin
Shin, J. M., Gwak, J. W., Kamarajan, P., Fenno, J. C., Rickard, A. H., & Kapila, Y. L. (2016) · Journal of Applied Microbiology · doi:10.1111/jam.13033 · Cited by 607
Yang, D., Biragyn, A., Hoover, D. M., Lubkowski, J., & Oppenheim, J. J. (2004) · Annual Review of Immunology · doi:10.1146/annurev.immunol.22.012703.104603 · Cited by 572
Metadata
- Authors
- Arnold, R. R., Cole, M. F., & McGhee, J. R.
- Venue
- Science
- Published
- 1977-07-15
- Volume
- 197
- Issue
- 4300
- Pages
- 263-265
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2009727907
- Cited by
- 676
- References
- 22
- FWCI
- 9.82
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: A Bactericidal Effect for Human Lactoferrin. https://app.cochat.ai/papers/10.1126/science.327545
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- Arnold, R. R., Cole, M. F., & McGhee, J. R. (1977). A Bactericidal Effect for Human Lactoferrin. Science. https://doi.org/10.1126/science.327545
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
