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Cited by 485

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Transgenic Animals

Jaenisch, Rudolf·1988·Science

Abstract

The ability to introduce foreign genes into the germ line and the successful expression of the inserted gene in the organism have allowed the genetic manipulation of animals on an unprecedented scale. The information gained from the use of the transgenic technology is relevant to almost any aspect of modern biology including developmental gene regulation, the action of oncogenes, the immune system, and mammalian development. Because specific mutations can be introduced into transgenic mice, it becomes feasible to generate precise animal models for human genetic diseases and to begin a systematic genetic dissection of the mammalian genome.

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Metadata

Authors
Jaenisch, R.
Venue
Science
Published
1988-06-10
Volume
240
Issue
4858
Pages
1468-1474
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W4236681559
Cited by
485
References
0
FWCI
22.30
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Transgenic Animals. https://app.cochat.ai/papers/10.1126/science.3287623
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Jaenisch, R. (1988). Transgenic Animals. Science. https://doi.org/10.1126/science.3287623

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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